A quickfire double from Ante Rebic and Brahim Diaz gave AC Milan a shock lead at Anfield in the Champions League.
Liverpool started like a house on fire and deservedly went in front via a Fikayo Tomori own goal from a Trent Alexander-Arnold cross.
The Reds were absolutely dominant and could and perhaps should have doubled their lead minutes later as Mohamed Salah missed a penalty for the first time since 2017.
The home side eventually tired and AC Milan settled and made the most of it.
Rebic finished off a fine move sweeping the ball past Alisson and as the away side were celebrating the goal, BT Sport's camera's cut away to Van Dijk who looked on with a look of shock on his face.
He summed up the frustration inside Anfield and it would only get worse as former Manchester City man Diaz turned it around.
Liverpool will desperately hope to turn it around in the second half as they aim to avoid disappointment in matchday one.
Salah did manage to get them back on level terms early in the second half.
He exchanged a one-two with Divock Origi but seemingly had to wait an age for the ball to drop low enough for him to poke past Maignan.