The Citizens played out a 1-1 home draw with Liverpool last weekend, while Spurs were condemned to their third successive league defeat by Aston Villa, losing 2-1 in North London, and here, Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER CITY vs. TOTTENHAM HOTSPUR
MANCHESTER CITY
Out: Kevin De Bruyne (hamstring)
Doubtful: Mateo Kovacic (thigh), Matheus Nunes (muscle)
Sports Mole's predicted XI: Ederson; Walker, Dias, Ake; Akanji, Rodri; Foden, Alvarez, Bernardo, Doku; Haaland
TOTTENHAM HOTSPUR
Out: Cristian Romero (suspended), Rodrigo Bentancur (ankle), James Maddison (ankle), Micky van de Ven (hamstring), Richarlison (pelvic), Manor Solomon (knee), Ivan Perisic (knee), Ryan Sessegnon (thigh), Ashley Phillips (ankle), Alfie Whiteman (ankle), Pape Matar Sarr (muscle)
Doubtful: None
Sports Mole's predicted XI: Vicario; Porro, Emerson, Davies, Udogie; Bissouma, Lo Celso; Johnson, Kulusevski, Gil; Son
For data analysis of the most likely results, scorelines and more for this match please click here.