Azerbaijan vs. Estonia (Saturday, 2.00pm)
Embroiled in a fight against relegation to the UEFA Nations League's lowest level, Azerbaijan and Estonia will clash in Qabala on Saturday afternoon.
Sitting third in League C Group 1, the Estonians will seal survival if they avoid defeat; while their hosts must win to defy the drop into League D.
We say: Azerbaijan 2-1 Estonia
A long-awaited win could be on the cards for Azerbaijan, as they have the benefit of home advantage and Estonia do not tend to travel well.
Neither side is watertight in defence, so goals are surely guaranteed at Qabala City Stadium, where the hosts can keep hopes of League C survival alive.
Georgia vs. Ukraine (Saturday, 5.00pm)
As closely contested League B Group 1 nears its conclusion, promotion - and relegation - rivals Georgia and Ukraine will meet in Batumi on Saturday evening.
Over the next few days, both sides could either step up to the UEFA Nations League's top tier or drop down to League C, after they experienced contrasting fortunes last month.
We say: Georgia 2-1 Ukraine
Two well-matched teams could be separated by one goal again, but home advantage should help Georgia over the line to victory, knocking Ukraine out of the promotion race.
The hosts may have an ageing defence, but Willy Sagnol has forged them into a solid team and their ability to counter-attack is renowned.
Montenegro vs. Iceland (Saturday, 5.00pm)
Montenegro welcome Iceland to Stadion Kraj Bistrice in Niksic for their penultimate League B Group 4 fixture in the UEFA Nations League on Saturday evening.
Both nations are at risk of suffering relegation to League C and they meet again just over two months on from Strakarnir okkar beating the Brave Falcons 2-0 in Reykjavik.
We say: Montenegro 1-1 Iceland
Montenegro will be out for revenge against Iceland and can ill-afford anything but a victory if they wish to avoid relegation to League C. However, we feel that the visitors will frustrate the hosts and come away with at least a share of the spoils.
Turkey vs. Wales (Saturday, 5.00pm)
Wales travel to the Kadir Has Stadium in Kayseri to face Turkey in their penultimate League B Group 4 fixture in the UEFA Nations League on Saturday evening.
Neither nations could be separated when they last met in September as they played out a goalless stalemate in Cardiff on matchday one.
We say: Turkey 2-1 Wales
Both nations will back themselves to come away with a positive result from Saturday's contest and they are aware of how important securing maximum points is in their quest to finish top of their group.
Another tight affair, like the reverse fixture, cannot be ruled out, but we can see the two teams scoring in this one and Turkey just edging it on home soil.
Andorra vs. Moldova (Saturday, 5.00pm)
Moldova can boost their hopes of securing promotion from League D Group 2 in the UEFA Nations League when they face fellow European minnows Andorra at Estadi Nacional on Saturday.
These two nations are among the six-lowest ranked teams in Europe, with Moldova placed 150th in the FIFA World Rankings and 20 positions higher than Andorra (170th).
We say: Andorra 0-1 Moldova
Fixtures between two European minnows tend to be low-scoring affairs and another is set to be in store on Saturday, although Moldova will be regarded as slight favourites and will back themselves to claim a slender victory to strengthen their hopes of promotion to League C.
Germany vs. Bosnia H'vina (Saturday, 7.45pm)
Needing just a point to all but guarantee a first-placed finish in League A Group 3 of the UEFA Nations League, Germany welcome Bosnia-Herzegovina to the Europa-Park Stadion in Freiburg on Saturday.
Julian Nagelsmann's side have already assured themselves of a spot in the quarter-finals, while their visitors are not completely out of contention despite an appalling set of results so far.
We say: Germany 3-0 Bosnia-Herzegovina
On Bosnian soil, the Golden Lilies gave Germany a decent run for their money and are now squaring up to a Mannschaft side whom Nagelsmann has conceded are nursing some bumps and bruises.
Nevertheless, Saturday's hosts should comfortably overwhelm their one-point visitors in a comprehensive victory, which would seal both sides' fates before the final matchday.
> Key defender banned, will Ortega start? Predicted Germany XI against Bosnia
Netherlands vs. Hungary (Saturday, 7.45pm)
Locked together on five points in League A Group 3 of the UEFA Nations League, the Netherlands and Hungary meet on Saturday in a winner-takes-all clash at the Johan Cruyff Arena.
Following a 1-1 draw between the two nations in October, the victor of the Amsterdam battle - if there is one - will guarantee a place in the quarter-finals alongside already-qualified Germany.
We say: Netherlands 1-0 Hungary
Saturday's intriguing battle ought to be as close as the standings suggest it will be, especially as the Netherlands are missing a chief creator in Simons who can unlock the most rigid of defences.
Hungary's best hope will surely be to hit Koeman's men on the counter, but the Dutch should break through the rearguard-heavy Magyars at least once before shutting up shop to nab a coveted quarter-final place.
> Will De Jong play after injury scare? Predicted Netherlands XI against Hungary
Albania vs. Czech Republic (Saturday, 7.45pm)
Both vying for promotion to the UEFA Nations League's top tier, Albania and League B Group 1 leaders Czech Republic will lock horns on Saturday evening.
The Czechs travel to Tirana having beaten their Albanian counterparts in Prague last month, taking them one point clear at the top with two rounds remaining.
We say: Albania 1-2 Czech Republic
In a finely balanced group, there is little to choose between all four nations, but Czech Republic have momentum on their side and may claim top spot.
Both teams are missing integral defenders, which might aid either attack, and several goals should be assured in Tirana.
Sweden vs. Slovakia (Saturday, 7.45pm)
Locked together at the top of League C Group 1 with two games to play, Sweden and Slovakia will battle it out to take the outright lead when they meet on Saturday evening.
Both unbeaten so far, following a 2-2 draw in last month's reverse fixture, either side will secure automatic promotion by beating the other in Solna.
We say: Sweden 3-2 Slovakia
Two attack-minded teams should share a few more goals this weekend, following their 2-2 draw in Slovakia last month, but Sweden are set to come out on top.
The hosts will simply have too much firepower for their visitors to handle - even if the Swedish defence still looks suspect.