Los Blancos beat Pachuca 3-0 on Wednesday to secure their second trophy of the campaign, but they were held to a 3-3 draw by Rayo Vallecano in their last domestic match, with the team currently third in the La Liga table, one point behind leaders Barcelona with a game in hand.
Sevilla, meanwhile, are 11th in Spain's top flight, and Garcia Pimienta's team will enter the clash off the back of a 1-0 victory over Celta Vigo.
Here, Sports Mole takes an in-depth look at the head-to-head record and previous meetings between the two sides ahead of their top-flight contest in the Spanish capital this weekend.
Head-to-head record
Previous meetings: 190
Real Madrid wins: 104
Draws: 32
Sevilla wins: 54
These two teams have met on 190 occasions throughout history, and it is Real Madrid that lead the head-to-head record, having won 104 times to Sevilla's 54, while there have also been 32 draws between the two teams.
Cristiano Ronaldo is comfortably the all-time leading goalscorer in this fixture, with the Portuguese netting an incredible 27 times against Sevilla during his time at Real Madrid.
Los Blancos have scored 404 goals against Sevilla, conceding 256, while they have unsurprisingly also been the dominant force in the La Liga meetings between the two sides, winning 87 of their 160 matches in Spain's top flight, losing 45.
Sevilla beat Real Madrid twice in 2018, but they are currently on an 11-game winless run against the capital giants, suffering nine defeats in the process, including a 1-0 reverse at Bernabeu last term.
There has not been much to separate the two teams in their recent contests, though, with seven of Real Madrid's last eight league wins over Sevilla coming by just the odd goal.
Not since December 2008 have Sevilla beaten Real Madrid away from home in the league, with the visitors triumphing in a seven-goal thriller.
Real Madrid have some big recent home wins over Sevilla to their name, meanwhile, notably a 5-0 success in December 2017 and a 7-3 triumph in October 2013.
Last 20 meetings
Feb 25, 2024: Real Madrid 1-0 Sevilla (La Liga)
Oct 21, 2023: Sevilla 1-1 Real Madrid (La Liga)
May 27, 2023: Sevilla 1-2 Real Madrid (La Liga)
Oct 22, 2022: Real Madrid 3-1 Sevilla (La Liga)
Apr 17, 2022: Sevilla 2-3 Real Madrid (La Liga)
Nov 28, 2021: Real Madrid 2-1 Sevilla (La Liga)
May 09, 2021: Real Madrid 2-2 Sevilla (La Liga)
Dec 05, 2020: Sevilla 0-1 Real Madrid (La Liga)
Jan 18, 2020: Real Madrid 2-1 Sevilla (La Liga)
Sep 22, 2019: Sevilla 0-1 Real Madrid (La Liga)
Jan 19, 2019: Real Madrid 2-0 Sevilla (La Liga)
Sep 26, 2018: Sevilla 3-0 Real Madrid (La Liga)
May 09, 2018: Sevilla 3-2 Real Madrid (La Liga)
Dec 09, 2017: Real Madrid 5-0 Sevilla (La Liga)
May 14, 2017: Real Madrid 4-1 Sevilla (La Liga)
Jan 15, 2017: Sevilla 2-1 Real Madrid (La Liga)
Jan 12, 2017: Sevilla 3-3 Real Madrid (Copa del Rey Round Five)
Jan 04, 2017: Real Madrid 3-0 Sevilla (Copa del Rey Round Five)
Aug 09, 2016: Real Madrid 3-2 Sevilla (UEFA Super Cup UEFA Super Cup)
Mar 20, 2016: Real Madrid 4-0 Sevilla (La Liga)
Last 10 La Liga meetings
Feb 25, 2024: Real Madrid 1-0 Sevilla (La Liga)
Oct 21, 2023: Sevilla 1-1 Real Madrid (La Liga)
May 27, 2023: Sevilla 1-2 Real Madrid (La Liga)
Oct 22, 2022: Real Madrid 3-1 Sevilla (La Liga)
Apr 17, 2022: Sevilla 2-3 Real Madrid (La Liga)
Nov 28, 2021: Real Madrid 2-1 Sevilla (La Liga)
May 09, 2021: Real Madrid 2-2 Sevilla (La Liga)
Dec 05, 2020: Sevilla 0-1 Real Madrid (La Liga)
Jan 18, 2020: Real Madrid 2-1 Sevilla (La Liga)
Sep 22, 2019: Sevilla 0-1 Real Madrid (La Liga)
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Written by
Matt Law