The UCL debutants suffered an agonising late defeat against Real Madrid on Wednesday, while Hoffenheim extended their winning run to three games with victory over FC Koln last time out.
Match preview
It is fair to say that Union Berlin could not have dreamed of a tougher way to begin their maiden Champions League campaign, as Urs Fischer's men experienced a baptism of fire against Real Madrid, who have lifted the famous trophy a record 14 times.
Not only did Union see just 24% possession while facing a barrage of 32 shots at the Bernabeu, but they also failed to register a single attempt on target, with Jude Bellingham breaking Die Eisernen hearts by scoring the only goal of the game deep into second-half stoppage time.
As a result, Fischer's side head into Saturday's clash on a three-game losing run across all competitions, with a 3-0 defeat to RB Leipzig and a 2-1 loss against Wolfsburg preceding Wednesday's Bernabeu failure, although Union remain within touching distance of the early Bundesliga frontrunners.
Having kicked off their campaign with successive 4-1 victories over Mainz and Darmstadt, Die Eisernen will be confident of returning to winning ways this weekend, although in-form Hoffenheim will back themselves to pile more pressure on Union Berlin.
Hoffenheim started their league campaign with a 2-1 defeat against Freiburg, but the Blues swiftly recovered from their opening-day loss, notching three consecutive wins to remain three points above Union in the early Bundesliga standings.
Following a 3-2 victory over Heidenheim, Pellegrino Matarazzo's men claimed a 3-1 win against Wolfsburg before securing a 3-1 triumph over FC Koln, with 20-year-old forward Maximilian Beier finding the back of the net in each of those victories.
Consequently, Hoffenheim have scored three goals in each of their previous three matches, picking up nine points along the way, while only the top two teams - Bayern Munich and Bayer Leverkusen - have accumulated more points than Die Kraichgauer this season.
Although Union Berlin avoided defeat in all 17 of their home league games last season - registering 11 wins and six draws in the process - Hoffenheim can take confidence from the fact that they boast a 100% record on the road this term, having already secured two away victories in 2023-24.
Union Berlin Bundesliga form:
Union Berlin form (all competitions):
Hoffenheim Bundesliga form:
Hoffenheim form (all competitions):
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Team News
There will likely be some tired legs in the Union Berlin camp following Wednesday's efforts against Real Madrid, meaning that Fischer could make several changes to the XI that started the game at the Bernabeu.
Having scored four goals in four Bundesliga appearances this season - including a hat-trick against Mainz on the opening weekend - Kevin Behrens will continue alongside Sheraldo Becker in the hosts' forward line.
With Laurenz Dehl (Achilles), Rani Khedira (calf), Robin Knoche (leg) and Andras Schafer (foot) sidelined through injury, Fischer has multiple selection headaches, but the shrewd manager will not stray from his favoured 3-5-2 formation.
Hoffenheim also have several injury absentees at the moment, as Marco John (ankle), Dennis Geiger (muscle) and Bambase Conte (fitness) remain on the treatment table ahead of Saturday's showdown.
Matarazzo could be tempted to stick with the same XI that instigated the club's third consecutive victory last weekend, with new signing Wout Weghorst partnering in-form striker Maximilian Beier in attack.
At the opposite end of the pitch, former Liverpool defender Ozan Kabak is expected to join John Brooks and Kevin Vogt in a back three, while goalkeeper Oliver Baumann will retain his place between the sticks.
Union Berlin possible starting lineup:
Ronnow; Doekhi, Knoche, Leite; Trimmel, Haberer, Laidouni, Kral, Gosens; Behrens, Becker
Hoffenheim possible starting lineup:
Baumann; Kabak, Brooks, Vogt; Kaderabek, Kramaic, Grillitsch, Promel, Skov; Weghorst, Beier
We say: Union Berlin 1-1 Hoffenheim
Aiming for a fourth successive win, Hoffenheim look set to frustrate Union Berlin, who will be fatigued after pushing Real Madrid all the way in midweek.