Both sides came away with maximum points from their respective most recent outings and will head into this weekend's encounter on a positive note.
Match preview
Morecambe ran out comfortable 5-1 winners against Doncaster Rovers in last Saturday's meeting between the teams at the Eco-Power Stadium.
Ged Brannan's men went into the interval with a two-goal following strikes from Eli King and Michael Mellon before Jacob Bedeau, David Tutonda and Mellon netted in the second-half to put the result beyond doubt.
Consequently, The Shrimps have moved up to eighth place in the League Two table, one point behind the last playoff place with a game in hand.
Lying in store next is the challenge of an opposing outfit who have won each of the last five editions of this fixture by a combined score of 13-0.
Unbeaten in six of their last seven home involvements leading up to Saturday's contest, the hosts have turned their turf into a fortress and will be confident of getting the job done this weekend.
Milton Keynes Dons simply had too much quality for Forest Green Rovers as they claimed a convincing 2-0 win at Stadium MK on Saturday afternoon.
Max Dean and Jack Payne found the back of the net in the opening 45 minutes to set Mike Williamson's men on their way to a well-deserved victory.
With 30 points picked up from their 20 matches this term, The Dons sit 11th in the standings but are firmly in playoff contention as they currently trail seventh-place Wimbledon by only one point.
Off the back of ending a six-game winless streak on the road last time out, Saturday's visitors will be seeking to secure consecutive wins away from home for the first time since the turn of the year.
Morecambe League Two form:
L
L
L
L
D
W
Morecambe form (all competitions):
L
L
L
W
D
W
MK Dons League Two form:
W
W
D
W
D
W
MK Dons form (all competitions):
D
W
W
D
L
W
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Team News
Morecambe's Michael Mellon boasts an impressive four goals from his last three matches and will be looking to come up with the goods once again.
With eight yellow cards to his name already, Adam Mayor is already walking another suspension tightrope this term and will need to keep his behaviour in check.
Twenty-four-year-old Jonathan Leko is back in contention for MK Dons after missing the win against Forest Green Rovers due to a slight knock.
Meanwhile, MJ Williams remains unavailable for selection for the visitors as he prepares to sit out a third straight game due to an ankle problem.
Morecambe possible starting lineup:
Smith; Tutonda, Bedeau, Connolly, Senior; Songo'o, King, McKiernan; Mayor, Bloxham, Mellon
MK Dons possible starting lineup:
MacGillivray; Norman, O'Hora, Lewington; Tomlinson, Payne, Robson, Grant, Harvie; Dean, Gilbey