The hosts, who occupy eighth position in the Turkish Super Lig table, will be aiming to end a six-game winless run.
Match preview
Kayserispor head into the penultimate game of the season off the back of a poor run of form, picking up just two points in six matches.
In their last two outings, Kayserispor have lost to Alanyaspor and Fatih Karagumruk, failing to score in both of those contests.
Although they have drawn a blank in consecutive matches, Cagdas Atan may have greater concerns about his side's recent defensive performances.
They have shipped 19 goals across their previous six matches, shipping at least three times in three of those contests.
Saturday's hosts have tended to offer stronger defensive performances at home, though, having kept seven of their nine clean sheets this season at the Kadir Has Stadium.
After their Turkish Cup final dreams were ended in the semi-finals by Istanbul Basaksehir, Ankaragucu returned to league action with a home fixture against Galatasaray.
Milson restored parity after Mauro Icardi had opened the scoring, but the Argentine grabbed his second before half time to give Galatasaray the advantage.
Ankaragucu were unable to mount a fightback in the second period, conceding two more goals as they fell to a 4-1 defeat that clinched Galatasaray the title and left Tolunay Kafkas' side in 13th position.
With two five points separating them from the relegation zone, Ankaragucu are well placed to secure survival, and they will want to guarantee their safety this weekend.
After winning 2-1 in the reverse fixture with Kayserispor, Ankaragucu will have the chance to complete a league double on Saturday.
Kayserispor Turkish Super Lig form:
L
D
L
D
L
L
Ankaragucu Turkish Super Lig form:
W
D
L
D
W
L
Ankaragucu form (all competitions):
L
L
D
W
D
L
Team News
Long-term absentee Nurettin Korkmaz remains sidelined for the hosts, while there are doubts over Lionel Carole's availability.
After being sent off last weekend, Yaw Ackah will miss out through suspension, which could present Anthony Uzodimma with a starting opportunity.
Miguel Cardoso is also suspended due to an accumulation of yellow cards, and he is set to be replaced by Bernard Mensah.
As for the visitors, they are still unable to call upon Uros Radakovic, who remains in the treatment room with a knee injury.
Kafkas could make a number of changes to his side, with Stelios Kitsiou, Matej Hanousek and Emre Kilinc all in contention for a starting berth.
After finding the net in each of his last three league appearances, Milson is expected to retain his place in the side.
Kayserispor possible starting lineup:
Akkan; Malcuit, Kizildag, Mujakic; Kitsiou, Dokanovic, Antalyali, Hanousek; Kilinc, Milson, Sowe
Ankaragucu possible starting lineup:
Bayazit; Sazdagi, Attamah, Kolovetsios, Kocaman; Uzodimma, Karimi; Kemen, Mensah, Mane; Thiam
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