The visitors, meanwhile, will have the chance to clinch a third consecutive league victory after beating Union Santa Fe and Lanus in their previous two Primera games.
Match preview
Huracan have experienced an encouraging start to the season, picking up eight points from their opening five league games.
The campaign began with a 2-0 away defeat to Racing Club, but Huracan have responded in style in their last four matches.
Rosario were beaten by two goals on matchday two before Sunday's visitors played out consecutive draws against Defensa y Justicia and Atletico Tucuman.
They extended their unbeaten run to four matches last weekend, with a Benjamin Garre strike helping Huracan clinch their first away league victory of the season.
Having conceded only one goal in their last four games, the visitors will believe that they have the defensive qualities to ward off the River Plate threat on Sunday.
River Plate enter the contest level on points with their hosts, and they have the chance to clinch a third consecutive league victory at the weekend.
The league campaign began with two draws and a defeat before they picked up their first win on matchday four after thrashing Union Sante Fe 5-1.
Three more points followed against Lanus, with goals from Jose Paradela and Braian Romero helping River Plate claim a 2-1 victory.
Despite winning their last two league matches, the visitors may be in downbeat mood after losing 1-0 to Velez Sarsfield in the Copa Libertadores in midweek.
With the second leg of their last 16 tie set to take place on Wednesday, River Plate will be looking for a confidence boost ahead of the home meeting with Velez Sarsfield.
Huracan Argentine Primera Division form:
Huracan form (all competitions):
River Plate Argentine Primera Division form:
River Plate form (all competitions):
Team News
The hosts are unable to call upon the services of Cesar Ibanez, who is set to be out for an extended period due to an anterior cruciate ligament injury.
After beating Colon in their last outing, Huracan are expected to keep changes to a minimum, although Rodrigo Cabral could return to the starting lineup.
Meanwhile, Matias Coccaro will continue to lead the line for the hosts, with the forward looking to open his account for the Primera season.
As for the visitors, Paulo Diaz is expected to keep his place in the centre of defence after starting the last two matches.
Elias Gomez dropped down to the bench for the midweek Copa Libertadores contest, but the left-back could return to the starting lineup for Sunday's encounter.
River Plate are also set to continue with a front two pairing made up of Braian Romero and Julian Alvarez.
Huracan possible starting lineup:
Chaves; Soto, Galvan, Merolla, Perez; Fattori, Hezze; Garre, Cristaldo, Cabral; Coccaro
River Plate possible starting lineup:
Armani; Mammana, Diaz, Martinez, Gomez; Paradela, Perez, Quintero, Fernandez; Romero, Alvarez