The hosts will enter the contest off the back of a 4-0 loss to the reigning champions, while Las Palmas played out a 1-1 draw with Osasuna in their last match at this level of football.
Match preview
Getafe will be pleased with what has been a solid campaign to date, boasting a record of eight wins, 10 draws and eight defeats from 26 matches, which has left them in 10th position in the table on 34 points.
The Deep Blue Ones, who have finished 15th in each of their last three La Liga campaigns, are only two points behind eighth-placed Las Palmas ahead of this weekend's contest, while they sit only six points from seventh-placed Real Sociedad on the same number of games (26).
Getafe will be aiming to put last weekend's 4-0 loss at Barcelona behind them, and they did record a 3-2 victory over Celta Vigo in their last game in front of their own fans on February 11.
Jose Bordalas's side have been impressive at home this season, winning seven of their 12 matches, collecting 24 points in the process, including victories in two of their last three.
Getafe will be looking to gain some revenge on Las Palmas on Saturday, meanwhile, having suffered a 2-0 defeat when the two teams locked horns for the reverse match earlier this season.
Las Palmas are also enjoying an impressive campaign, boasting a record of 10 wins, six draws and 10 defeats from 26 matches, which has left them eighth in the table on 36 points.
Pio Pio are only six points behind sixth-placed Real Betis in the race for the European spots, and it would be a remarkable achievement if they could sneak into the top six this season.
Garcia Pimienta's side, who finished second in the Segunda Division last term, will enter this match off the back of a 1-1 draw with Osasuna, with Kirian Rodriguez cancelling out an opener from Unai Garcia.
Las Palmas have found it difficult to show consistency on their travels this season, picking up just 14 points from 13 matches, while they lost 5-0 at Atletico Madrid in their last away game on February 17.
The team's success this season has been built on a solid defence, only conceding 26 times in their 26 matches, but they have only netted 26 times, which is the sixth-worst attacking record in the division.
Getafe La Liga form:
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Las Palmas La Liga form:
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Team News
Getafe will again be missing Mauro Arambarri due to an ACL injury, while Jordi Martin remains a major doubt for the capital outfit, as he battles a shoulder problem.
The home side will also have to work around the absences of Djene Dakonam and Omar Alderete, as the pair are both suspended after picking up milestone bookings in the loss to Barcelona last time out.
Domingos Duarte and Jose Angel Carmona are likely to be introduced into the back four, while Jaime Mata and Oscar Rodriguez could also be brought into the starting side for this match.
As for Las Palmas, Eric Curbelo, Alvaro Lemos and Pejino are again set to miss out through injury, while Alex Suarez is suspended due to the booking he picked up against Osasuna.
There will be a return to the squad for Maximo Perrone, though, with the Argentine available after missing the team's 1-1 draw last time out due to a one-game ban.
Head coach Garcia Pimienta will make changes from the side that started against Osasuna, with Sandro Ramirez, Munir El Haddadi and Julian Araujo all in line for recalls.
Getafe possible starting lineup:
Soria; Iglesias, Alvarez, Duarte, Carmona; Greenwood, Maksimovic, Milla, Mata; Mayoral, O Rodriguez
Las Palmas possible starting lineup:
Valles; Araujo, Coco, Marmol, S Cardona; Park, Perrone, Loidoice, K Rodriguez, Munir; Sandro
We say: Getafe 2-1 Las Palmas
This is a really tough one to predict, and we came close to picking a draw, but Getafe have won seven times at home this season, while Las Palmas have suffered seven defeats on their travels, and we believe that the capital outfit will be able to navigate their way to an important three points here.