He's no longer in the Premier League after spells with Chelsea, Manchester United, and Tottenham Hotspur but he remains as relevant as ever in Italy with Roma.
The 58-year-old is always relishing new challenges and the Stadio Olimpico he has already made an impact.
Capital club Roma sit fourth in Serie A after seven games, with five wins and two losses, while summer signing Tammy Abraham has two goals and two assists in that time.
And the Giallorossi's recent 2-0 victory over Empoli, thanks to goals from Lorenzo Pellegrini and Henrikh Mkitaryan, extended Mourinho's unbeaten run on home soil in Serie A to 42 matches.
The record includes his stint at Inter Milan but is, nonetheless, hugely impressive.
The Special One's streak beats Massimiliano Allegri's two-year unbeaten run during his first spell at Juventus, from September 2015 to September 2017.
Mourinho holds the same record in the Premier League having not lost in 78 games on home soil at Chelsea between 2004 and 2007, where he delivered back-to-back league titles.
It's an accomplishment that has been one of the highlights of Mourinho's managerial career.
This impressive record was down to his pragmatism and helped him to achieve unprecedented success in England upon his arrival.
His tough time at Tottenham may have had some believing his time at the top of footblal was coming to a close.
But he's indicating it's not the end of an era for Mourinho.
His new record shows he's still got the prowess to succeed at Roma.