The 27-year-old had initially been charged with four counts of rape in August and now faces a total of six allegations of rape.
Mendy has been in custody since his arrest after a number of bail applications were made but refused by judges.
He is also charged with a single count of sexual assault, Cheshire Police said in a statement.
All the alleged offences relate to four women over the age of 16 and are alleged to have taken place between October 2020 and August 2021.
The statement from police added: "Cheshire Constabulary and the Crown Prosecution Service would like to remind everyone that criminal proceedings against Matturie and Mendy are live and that they have a right to a fair trial."
Mendy, who is currently on remand at HMP Altcourse in Liverpool, is summonsed to appear at Stockport Magistrates' Court on Wednesday.
The left-back has played for Manchester City since 2017, when he joined from Monaco for a reported fee of £52million.
He was suspended by the club after being charged by police, pending an investigation.
Mendy, alongside co-accused Louis Saha Matturie, 40, is scheduled to go on trial on January 24, 2022.