The Reds were winners of the competition in 2021 but surrendered the trophy during a 3-2 loss to Manchester City last season.
The game was Liverpool's first since returning from the World Cup and began a horror start of form in 2023 as arch-rivals Man United went on to win the cup.
Jurgen Klopp's side are still record nine-time winners of the EFL Cup and will be eyeing another run after a strong start to this season.
Liverpool actually dumped out Leicester during their road to Wembley two years ago having come from two goals down to claim a penalty shootout victory.
But Leicester will fancy their chances at revenge after making light work of their return to the Championship.
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The Foxes have recorded seven wins and one draw from their opening eight games to propel them to the top of the table.
Liverpool vs Leicester: talkSPORT coverage
This Carabao Cup third round clash will take place on Wednesday, September 27.
Kick-off at Anfield is scheduled for 7.45pm.
talkSPORT 2 will have live coverage of the showdown in Liverpool, with Sam Matterface and Micky Gray providing commentary.
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Liverpool vs Leicester: Team news
The hosts are still sweating on the fitness of Trent Alexander-Arnold after he missed their last two games with a hamstring injury.
Thiago Alcantara is still weeks away from a comeback from a lengthy hip issue while Caoimhin Kelleher is expected to start in goal.
Leicester could hand Conor Coady a first start against his former club after recovering from a foot issue.
Kelechi Iheanacho could be restored to lead the line with veteran Jamie Vardy afforded a rest.
Liverpool vs Leicester: What has been said?
Klopp has hailed the improvement Darwin Nunez has made this season.
"He has made massive steps in the last few weeks. He is a threat. You all saw the goal, that was probably pretty good, right? That was really strong," Klopp said.
"Incredible. Everybody is looking at me when I talk about the goals but these eyes - I saw it only once - can't wait to see it properly back.
"He was always available. It's super-important for us now that we have a ball player: chip the ball (into him), get it on the chest and play from there.
"That's how we scored the third goal at Wolves, super-important for us. The defensive work he puts in is probably the main difference.
"He always wanted (to do it) but it was less coordinated. Now that looks much better.
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"We have found a way to do it around him, Curtis (Jones) and Dom (Dominik Szoboszlai) help a lot, how flexible they are in that way. It's really good, absolutely."
Liverpool vs Leicester: Match facts
Leicester have kept a clean sheet in five of their last six League Cup games, with the exception being a 2-0 loss to Newcastle United last season.
Liverpool have won 17 of their last 18 League Cup ties against sides from a lower division, with the exception being a penalty shootout defeat to Northampton in September 2010 under Roy Hodgson.
Leicester are winless in their last 13 away games against Liverpool in all competitions (D3 L10). However, only Man City (6) have beaten Jürgen Klopp's Reds more often than Leicester (5) since the German took charge.
Liverpool have progressed from two of their three League Cup meetings with Leicester, failing only in 2017-18. They've ended up reaching the final on both previous occasions they've beaten the Foxes (1986-87 and 2021-22).