The Argentine has had one of the most successful careers in football, winning near enough every big trophy on offer - including the World Cup in December.
Messi finally lifted the trophy in Qatar when Argentina beat France in a pulsating 3-3 final in Doha that the Albiceleste won on penalties.
It adds to an already hefty trophy cabinet that contains LaLiga, Ligue 1 and Champions League titles.
And that also includes seven Ballon d'Or accolades - while he is the favourite to go on and win an eighth this year.
But since leaving Paris Saint-Germain this summer and penning a deal with Inter Miami, he might have left his new club somewhat peeved with his latest comments.
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The 35-year-old admitted that he felt he had nothing left to achieve in football having ultimately won the lot.
He said: "Does the Ballon d'Or matter to me? No, it's no longer important to me.
"I've always said; the individual prizes are not what matters to me.
"The collective ones are the most important. The most important prize at the moment is the World Cup, the greatest prize for me [2022] was my last World Cup.
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"I will see how things go, but in principle, no, I will not go to the next World Cup.
"I have achieved everything in football. There is nothing left."
Messi has never played out of Europe in club football having spent most of his career at Barcelona before two years with PSG.
It means that there are plenty of trophies up for grabs as he prepares on his new journey with Inter Miami.
There is the MLS Cup, which goes to the league's outright champion at the end of their playoffs.
However, Inter Miami currently find themselves bottom of their particular division while Phil Neville was recently sacked as a result.
And on the continent, there is the CONCACAF Champions Cup up for grabs - though American sides have not fared well in the competition and have won it just once.
Seattle Sounders lifted the trophy in 2022, though LA Galaxy and D.C United have also win the tournament before it was rebranded in 2008.