The Foxes boss has confirmed that Abdul Fatawu will be missing for the rest of the season with the ACL injury he picked up over the international break, and he joins Ricardo Pereira (thigh) and Jakub Stolarczyk (ankle) in the medical bay.
In addition, Facundo Buonanotte serves a one-game ban for an accumulation of bookings, and there are doubts about the fitness of Jamie Vardy (back), Bobby Decordova-Reid (Achilles) and Jordan Ayew (knee).
One piece of good news arrives in the shape of Patson Daka, who has been cleared to make his first appearance of the season by Cooper, but it may be too soon to throw him in from the start.
As a result, Odsonne Edouard could be brought back in from the cold as part of a new-look front three with Stephy Mavididi and Bilal El Khannouss, although Kasey McAteer is another option.
It may be all change up front for Leicester, but the spine of the team should remain untouched, as Harry Winks, Boubakary Soumare and Wilfred Ndidi should all reprise their roles in midfield.
The same applies to James Justin, Victor Kristiansen, Wout Faes and Jannik Vestergaard at the back, as the unaltered quartet protect number one shot-stopper Mads Hermansen.
Leicester City possible starting lineup:
Hermansen; Justin, Faes, Vestergaard, Kristiansen; Winks, Ndidi, Soumare; El Khannouss, Edouard, Mavididi