La Liga chair Javier Tebas has revealed Barcelona, Real Madrid and Juventus are plotting to revive the European Super League.
The initial plan - which included six Premier League clubs - failed spectacularly in April following wide-spread protests from fans.
The ESL guaranteed its 12 founding members - later dubbed the "Dirty Dozen" - entry into the lucrative competition each season.
Critics slammed the idea for eliminating European football's promotion system that's been in place for more than a century.
Gary Neville, one of the main critics of ESL, said in April: "It's an absolute disgrace and we have to wrestle back the power in this country from the clubs at the top of this league.
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"It's pure greed, they're imposters, the owners... they have nothing to do with football in this country.
"There are 100-odd years of football in this country with fans that have lived and loved these clubs and they need protecting, the fans need protecting."
Manchester United, Manchester City, Arsenal, Tottenham, Chelsea and Liverpool were the first to withdraw from the ESL, just days after it's announcement.
That caused the initial proposal to collapse and, according to Tebas, Premier League clubs will be barred from entering the ESL as a result.
Speaking to Marca, Tebas said: "The three castaways [Barcelona, Real and Juventus] who remain with the flag are talking and I can tell you ahead: they already know that the English are not going to be there.
"Now they are setting up a kind of Super League with the rest of the leagues so that the enemy is not only the Champions League, but also the Premier."
If the ESL was to go ahead, it would have a detrimental impact on domestic leagues as the fight for European qualification would be eliminated.
There would be less competition for places, meaning only the title race and relegation battle - along with derbies - would matter.
And Tebas remains concerned by the threat of the ESL, believing the likes of Real and Barcelona are only popular because of their historical roots.
He added: "The Super League that we saw in April worries me zero, but the concept does. They think that in football the big clubs have to rule... there is a lot of selfishness there.
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"It is true that they are big, but where have they become big? Competing against Osasuna, Betis... and they can't put them aside now."
On how the ESL would impact domestic leagues financially, Tebas added: "It would mean, to the Spanish League, lose about €1.2billion. The leagues are united, even the Premier."
Real president Florentino Perez has previously promised to revive the ESL. He said in April: "If anyone thinks the Super League is dead, are they wrong? Absolutely.
"We're going to keep working and what everyone thinks is for the best will emerge. The project is on standby. The Super League still exists."