With John McGinn having been ruled out for a number of weeks with a hamstring injury, Emery was always going to be forced into an alteration.
Having rotated his squad for Wednesday's EFL Cup tie at Wycombe Wanderers, several players had put themselves into contention to be brought into the midfield.
The likes of Ross Barkley and Emiliano Buendia were both realistic options, but Emery has instead opted for Leon Bailey who is yet to provide a goal or assist this campaign.
Jhon Duran is also made to wait for his first Premier League start of the season despite his four goals in 131 minutes of top-flight football this campaign.
Villa will move into second place in the Premier League standings if they can prevail at Portman Road.
Ipswich make three changes
As for Ipswich, head coach Kieran McKenna has decided to make three changes to the team that posted a 1-1 draw at Southampton last weekend.
Kalvin Phillips, Jack Clarke and Chiedozie Ogbene - all new signings - have been brought into the midfield and final third respectively.
Jens Cajuste, Wes Burns and Sammie Szmodics are the players to make way, the former not being selected in the squad.
The Tractors Boys will move into 13th place in the table if they can record their first win since returning to the Premier League.
Ipswich Town XI: Muric; Tuanzebe, O'Shea, Greaves, Davis; Morsy, Phillips; Ogbene, Hutchinson, Clarke; Delap
Subs: Walton, Johnson, Townsend, Luongo, Taylor, Burns, Chaplin, Szmodics, Hirst
Aston Villa XI: Martinez; Konsa, Carlos, Torres, Digne; Tielemans, Onana; Bailey, Rogers, Ramsey; Watkins
Subs: Gauci, Nedeljkovic, Maatsen, Bogarde, Philogene, Swinkels, Barkley, Buendia, Duran