Lee Carsley's men begin the tournament as one of the favourites, having picked a strong squad packed with Premier League players.
England last won this competition in 1984 and you can follow their progress this summer for free.
England U21s vs Czech Republic U21s: How to watch
Unfortunately, no UK-based TV company decided to bid for the rights to show the Young Lions in action.
Instead, games will be available to stream for free via the UEFA website.
England U21s vs Czech Republic U21s: How to listen
talkSPORT 2 will have live coverage from the Batumi Arena in Georgia, with kick-off scheduled for 5pm UK time.
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Commentary will come from 0lly Clink and former England international David Nugent.
talkSPORT.com will also have a live blog to take you through all the action as well.
To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream.
You can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
England U21s vs Czech Republic U21s: Team news
Levi Colwill might not play a part in the first group game, as he was called up to England's senior team, and joined the group late.
But Emile Smith Rowe is expected to be fully fit and ready to contribute despite a disrupted campaign at Arsenal.
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England U21 Squad in full
Goalkeepers: Josh Griffiths (West Bromwich Albion), Carl Rushworth (Brighton and Hove Albion), James Trafford (Manchester City)
Defenders: Max Aarons (Norwich City), Jarrad Branthwaite (Everton), Levi Colwill (Chelsea), Charlie Cresswell (Leeds United), Taylor Harwood-Bellis (Manchester City), Ben Johnson (West Ham United), Luke Thomas (Leicester City)
Midfielders: Tommy Doyle (Manchester City), Harvey Elliott (Liverpool), James Garner (Everton), Angel Gomes (Lille), Curtis Jones (Liverpool), Jacob Ramsey (Aston Villa), Oliver Skipp (Tottenham Hotspur)
Forwards: Cameron Archer (Aston Villa), Morgan Gibbs-White (Nottingham Forest), Anthony Gordon (Newcastle United), Noni Madueke (Chelsea), Cole Palmer (Manchester City) Emile Smith Rowe (Arsenal)
England U21s vs Czech Republic U21s: What has been said?
England boss Carsley is confident his side can win the Euros.
Speaking after the squad announcement, he said: "We feel quite confident about the squad.
"We tried to pick as many players who have been playing, particularly towards the end of the season and we've got plenty of players who have been and there's plenty of caps in there.
"Stats would tell you from past U21 tournaments that we haven't won it since 1984 and we're rated sixth or eighth in the coefficient rankings, so to win it we're going to have to perform above where our ratings are at the minute.
"I'm confident in the group, I feel like we're in a good position and we're going to go out there and really attack every team and I'm confident we can do well."