Alaba has missed his side's last two matches against Girona and Napoli due to a groin problem, but he is believed to have a chance of being involved in this weekend's clash.
Los Blancos are already definitely without the services of two centre-backs, as Eder Militao is a long-term absentee due to a serious knee injury, while Nacho is suspended due to his red card in the 3-0 victory over Girona in the league last weekend.
Real Madrid will also again be missing Thibaut Courtois (knee) and Arda Guler (thigh), but the team did not pick up any fresh fitness issues in Tuesday's 3-2 win over Napoli in the Champions League.
Ferland Mendy came off the bench against Napoli and could now potentially be in line for his first start of the season at left-back, while Fran Garcia is also an option in that area.
Eduardo Camavinga has recently been used at left-back but could now be moved into central midfield, with Toni Kroos potentially dropping to the bench.
Jude Bellingham scored his eighth goal of the campaign against Napoli and will again play as the number 10 behind a likely front two of Rodrygo and Vinicius Junior.
Rodrygo has only scored once this season but is expected to again be given the nod over Joselu despite the fact that the Spaniard has four league goals to his name in 2023-24.
Real Madrid possible starting lineup: Kepa; Carvajal, Rudiger, Alaba, Mendy; Valverde, Tchouameni, Camavinga; Bellingham; Vinicius, Rodrygo