The South American giants will also travel to North Africa without notable names such as Alisson Becker, Raphinha, Gabriel Martinelli and Bruno Guimaraes, as interim manager Ramon Menezes has shaken up the squad.
In Alisson Becker's absence, Manchester City goalkeeper Ederson will start between the sticks in Tangier, with Eder Militao and Gleison Bremer expected to partner one another at centre-back.
Renan Lodi and Emerson Royal are likely to occupy the full-back spots, while Lucas Paqueta and Casemiro could be joined in midfield by Andrey Santos, who scored six goals at the South American U-20 Championship earlier this year.
Santos is one of nine players in the Brazil squad without a senior international cap, with Vitor Roque, Robert Renan and Mycael joining the Chelsea youngster on the latest roster.
Tottenham Hotspur's Richarlison has been forced to withdraw from the squad due to injury, so Vinicius Junior, Rodrygo and Antony all look set to start on Saturday, giving Selecao bags of skill and energy in attack.
Fellow forwards Yuri Alberto and Rony will be ready to make an impact off the bench, while Wolverhampton Wanderers' Joao Gomes could also be called upon if Menezes needs to shuffle his pack on the night.
Brazil possible starting lineup: Ederson; Lodi, Bremer, Militao, Royal; Paqueta, Casemiro, Santos; Vinicius, Rodrygo, Antony