Kasper Hjumland's side breezed through their qualification for the tournament and are now seen as dark horses to go far this winter.
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The Danes made it to the semi-finals of Euro 2020 in their last major tournament and now they will test themselves in football's showpiece.
They face the Carthage Eagles, who beat Mali in a two-legged play-off to qualify, in their opening game.
Jalel Kadri's side were knocked out in the group stage of the 2018 World Cup and will be hoping to make it out this time around.
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Denmark vs Tunisia: talkSPORT coverage
This World Cup Group D clash will be played on Tuesday, November 22.
Kick-off at the Education City Stadium in Al Rayyan is scheduled for 1pm.
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Hugh Woozencroft will be your host and live commentary will come from Alex Crook and former England striker Dean Ashton.
To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream.
ou can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
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Denmark vs Tunisia: Squad and team news
talkSPORT will bring you all the latest team news from the entire World Cup throughout November and December.
Denmark
21-man squad (Five more to be decided before deadline).
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Goalkeepers: Kasper Schmeichel, Oliver Christensen.
Defenders: Simon Kjaer, Joachim Andersen, Joakim Maehle, Andreas Christensen, Rasmus Kristensen, Jens Stryger Larsen, Victor Nelsson, Daniel Wass.
Midfielders: Thomas Delaney, Mathias Jensen, Christian Eriksen, Pierre-Emile Hojbjerg.
Forwards: Andreas Skov Olsen, Jesper Lindstrom, Andreas Cornelius, Martin Braithwaite, Kasper Dolberg, Mikkel Damsgaard, Jonas Wind.
Tunisia
To be confirmed
Denmark vs Tunisia: Match facts
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Full match stats will follow closer to the tournament.
talkSPORT will bring you all the latest stats and facts for each match in the competition so you can be fully prepared for every clash.