While Rodrigo Bentancur will serve the third of his seven-game domestic suspension, Guglielmo Vicario (ankle), Micky van de Ven, Richarlison, Wilson Odobert (all hamstring) and Mikey Moore (illness) all remain in the treatment room.
Thursday's game may also come too soon for Cristian Romero, who has missed the last three games with a toe injury, but Ange Postecoglou is hopeful that Dominic Solanke and Archie Gray will be fit to feature.
While Gray was forced off in the closing stages of Tottenham's 1-1 draw with Fulham last weekend with a knock/dead leg, Solanke missed out altogether through illness, but he should be fit to feature against his former club Bournemouth.
A return in attack for Solanke would likely see Timo Werner make way and would also allow Son Heung-min to move over to his favoured left flank, while Brennan Johnson, who scored the opener against Fulham, is set to continue on the right.
James Maddison, Pape Matar Sarr and Yves Bissouma all started in centre-midfield last time out, but one of those three is expected to be replaced by Dejan Kulusevski.
A back four of Pedro Porro, Radu Dragusin, Ben Davies and Destiny Udogie will likely remain intact, protecting goalkeeper Fraser Forster.
Tottenham Hotspur possible starting lineup: Forster; Porro, Dragusin, Davies, Udogie; Kulusevski, Bissouma, Maddison; Johnson, Solanke, Son
Written by
Oliver Thomas