There is just one point between these teams at the moment, and there is little to split them after the opening section of the season.
Match preview
Atlanta United might be one place below their opponents this weekend, but three points would not only guarantee they leapfrog them but could push them as high as third, depending on other results.
Considering how tight the league table is in the early stages of the season, a string of consistent results for the Five Stripes has the potential to have a huge impact.
Gonzalo Pineda's men head into Saturday with three consecutive games without a loss, although their previous two matches have both ended in draws.
The most recent one finished 2-2 against Philadelphia Union, a result that will have frustrated the Five Stripes fans after they watched their team throw away a two-goal lead.
Despite that, Atlanta should have plenty of confidence for this weekend, considering they have yet to be beaten at home this season.
Cincinnati will attempt to change that, and they have been slightly stronger on the road throughout this campaign, even though they have been dealing with a lack of goals.
The visitors have only scored six times across four away matches, an area that Pat Noonan will concentrate on fixing for the rest of the season.
Despite the lack of goals, the Orange and Blue have picked up consistent results across their opening eight fixtures, which has led them to fifth place heading into this weekend.
A victory could see them climb as high as second in the Eastern Conference, but they will need to put forward a more robust performance than last weekend when CF Montreal defeated them 2-1.
With that result marking two losses on the bounce and three without a win, the pressure will be heating up this weekend as Cincinnati focus on getting the season back on track.
Atlanta United Major League Soccer form:
W
W
L
W
D
D
FC Cincinnati Major League Soccer form:
D
W
W
D
L
L
FC Cincinnati form (all competitions):
L
W
W
D
L
L
Team News
Atlanta will continue without Jamal Thiare and Derrick Williams, who are expected to be sidelined for another three weeks.
They are joined in the medical room by Stian Gregersen, who is currently recovering from meniscus surgery, which is set to keep him out of action for a while.
The visitors also have injury concerns to contend with as goalkeeper Roman Celentano is still not fit enough to feature, but is closing in on a return to action, while London Aghedo is also unavailable.
Yuya Kubo should retain his place in the team after scoring in consecutive matches for the first time since joining Cincinnati, bringing plenty of confidence in front of goal this weekend.
Atlanta United possible starting lineup:
Guzan; Lennon, Cobb, Abram, Wiley; Muyumba, Slisz; Lobzhanidze, Almada, Etienne; Thiare
FC Cincinnati possible starting lineup:
Kann; Hagglund, Miazga, Murphy; Yedlin, Kubo, Bucha, Nwobodo; Acosta, Boupendza; Baird
We say: Atlanta United 1-1 FC Cincinnati
There is very little to split these two teams in the league table, and that is something that could end up being reflected in the match this weekend.
Cincinnati has struggled in recent weeks, and that is something that they need to turn around as soon as possible, but Atlanta's strengths could lead to them sharing the spoils.