Jurgen Klopp's meek men were torn to shreds in their opening battle at Anfield last week, where Gianluca Scamacca's brace and a Mario Pasalic strike propelled La Dea to an emphatic 3-0 victory.
The Reds' misery was prolonged with yet another home defeat at the weekend, as a 1-0 loss to Crystal Palace leaves Thursday's visitors two points behind new Premier League leaders Manchester City in the table.
Here, Sports Mole rounds up Liverpool's latest injury and suspension news ahead of their clash with Atalanta, who return to Serie A action at home to Hellas Verona on Monday night.
Conor Bradley
Status: Major doubt
Type of injury: Foot
Possible return date: April 18 (vs. Atalanta)
Conor Bradley's afternoon against Crystal Palace came to a premature end due to a foot injury, which he sustained while overstretching. The Reds are still waiting to learn the extent of the damage, but Klopp conceded that the young right-back was in a lot of pain, so it would come as a surprise to see him make the cut this week.
Thiago Alcantara
Status: Out
Type of injury: Muscle
Possible return date: Unknown
Thiago Alcantara waited 10 months to make his return from a hip injury, only to suffer a severe muscular problem on his comeback appearance against Arsenal in February, which could spell the end of both his season and his Liverpool career.
Ben Doak
Status: Out
Type of injury: Knee
Possible return date: Unknown
Ben Doak is yet to feature in 2024 due to the severe knee injury he picked up while representing the Under-21s in December, and he will be recovering from surgery for at least another several weeks.
Joel Matip
Status: Out
Type of injury: Knee
Possible return date: Unknown
Likewise, Joel Matip damaged his ACL in December and will not play again before the season concludes, meaning that the soon-to-be free agent may have also been seen in Liverpool colours for the final time.
LIVERPOOL'S SUSPENSION LIST
Liverpool have no players suspended for the second leg.