The hosts are winless in their last eight games across all competitions, while their visitors boast just one triumph from their last 10 matches.
Match preview
Al Khaleej fell to a 2-1 defeat against Abha when the sides went head-to-head at the Prince Sultan bin Abdul Aziz Stadium on Thursday evening.
Pedro Emanuel's men trailed to Francois Kamano's opener 11 minutes shy of half time but managed to draw level through Abdullah Al Salem before Fabian Noguera decided the game in stoppage time.
Consequently, Al-Danah remain 11th in the Saudi Pro League table, four points adrift of a place in the top half and six clear of the drop zone.
Next up is the task of facing off against an opposing outfit who have come out on top in just one of their last six editions of this fixture.
Having failed to win any of their last seven home matches, Monday's hosts will be keen to give their fans reason to cheer this time around.
Al Riyadh had to make do with a point for the fourth game running following a 2-2 stalemate against Al Nassr at the Prince Faisal bin Fahd Stadium.
Odair Hellmann's men found themselves behind inside 15 minutes to Otavio's opener before turning the game around through strikes from Andre Gray and Mohammed Al Aqel, only for Meshari Al Nemer to restore parity late on.
With 32 points picked up from 33 league matches this term, Al Riyadh sit 14th in the standings, just one point clear of relegation danger.
Aiming to record what would be only a first away triumph since early March, Monday's visitors have it all to do as they look to pull away from the drop zone.
Al Khaleej Saudi Pro League form:
D
L
D
L
D
L
Al Riyadh Saudi Pro League form:
L
W
D
D
D
D
Team News
Al Khaleej's Naif Masoud made his return to action from a one-game suspension last time out and is expected to retain his place in the XI here.
Mohamed Sherif has found the back of the net in both of his last two home appearances and will be looking to come up trumps for the hosts once again.
Mohammed Al Aqel will head into Monday's contest with the wind in his sails, having opened his Al Riyadh account at the 18th time of asking against Al Nassr.
Uruguayan international Martin Campana was hauled off with an injury scare in the aforementioned game and remains a major doubt for the visitors.
Knowledge Musona has missed each of his side's last two matches through injury, but the 33-year-old forward is not far off a return to action.
Al Khaleej possible starting lineup:
Sehic; Rebocho, Lopez, Masoud, Al Hamsal; Rodrigues, Jung, Hamzi; Narey, Sherif, Martins
Al Riyadh possible starting lineup:
Al Shammeri; Al Shuwayyi, Al Shwirekh, Asiri, Ali Alnowaiqi; Al Shehri, Ndong, Al Rashidi, Al Khaibari; Al Aqel, Gray