National team manager Vincenzo Montella included both Soyuncu and Unal in his initial 35-man selection for Euro 2024, and the two players were set to feature at this summer's tournament.
However, Atletico Madrid's Soyuncu picked up a thigh injury while representing loan club Fenerbahce last Sunday, and he has since been removed from the squad.
The 28-year-old has been capped on 55 occasions by Turkey, scoring twice, and he will allegedly be missing for at least three weeks, forcing Turkey to drop him from the selection.
Montella's side suffered a further blow on Friday when it was revealed that Unal had suffered a fractured toe on his left foot, ruling him out of the European Championship.
Unal, 27, has only managed three goals in 33 caps for his country, but the striker made a positive impression for Bournemouth in the second half of last season after arriving from Getafe.
Turkey will begin their Euro 2024 campaign against Georgia on June 18, before facing Portugal and the Czech Republic in their final two matches in Group F.
However, the Crescent-Stars will first tackle Italy and Poland in two warm-up fixtures.
Monaco 
Stade Brestois 29 
Bordeaux 
Nimes 
Bayern Munich 
FC Augsburg 
Paris Saint Germain 
Toulouse 
CSKA Moscow 
FC Rostov 
Leicester 
Chelsea 
Valencia 
Betis 
Dynamo Kyiv 
Chornomorets Odesa 
Verona 
Inter 
Bayer Leverkusen 
FC Heidenheim 
Borussia Dortmund 
SC Freiburg 
VFL Wolfsburg 
Union Berlin 
Arsenal 
Nottingham Forest 
Everton 
Brentford 
Spartak Moscow 
Lokomotiv Moscow 
Rangers 
Dundee Utd 
Atletico Madrid 
Alaves 
Lens 
Marseille 
Ingulets Petrove 
Shakhtar Donetsk 
AC Milan 
Juventus 
ST Malo 
Manchester City 
Tottenham 
Eintracht Frankfurt 
Werder Bremen 
Girona 
Espanyol 
Feyenoord 
Heerenveen 
ST Etienne 
Montpellier 
Grenoble Foot 38 
Heart Of Midlothian 
Celtic 
Reims 
Lyon 
PSV 
Groningen