Opta's Supercomputer has predicted Ruben Amorim's side to avoid the drop despite being 15th in the table with their last outing a 1-0 loss against Tottenham on Sunday.
United's defeat was their 12th in the league this season having amassed just 29 points from 25 matches.
They're 12 points clear of the bottom three and the latest predictions from Opta suggest that relegation can almost be ruled out entirely.
However, United are still on course for a bottom-half finish and one that would make unwanted history at Old Trafford.
Hope for United
According to the updated forecast in Opta's Supercomputer, United are most likely to finish 14th with a probability of 19 per cent.
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This is six spots below their eighth-place final standing at the end of last season, the worst in their Premier League history.
United have a 17.3 per cent chance of coming 13th and 17.9 per cent likelihood of ending up in 15th for the 2024/25 campaign.
Amorim's side are predicted to have just a 0.1 per cent chance of being relegated in 18th, with the prospect of 19th or 20th at zero.
However, they are set to miss out on the top five entirely, meaning they're likely to miss out on Europe next season.
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United still have a slim chance of Europa League football if they finish sixth, though this currently has a 0.1 per cent chance of occurring. Their best hope of Europa League football would be through winning the FA Cup.
Qualification could also arise if the Premier League claim a fifth spot for the Champions League as per their association club coefficient.
Battle for top five
With another Champions League spot potentially up for grabs, the summit of the table will change from a top four to a top five race.
Liverpool remain the firm favourites to come top and therefore win the Premier League title thanks to a forecast of 85.8 per cent.
Arsenal are seven points behind them in the table and their closest rivals with a probability of 14.1 per cent to finish second.
Despite their struggles earlier in the season, Manchester City have a whopping 53.2 per cent chance of finishing third.
Nottingham Forest look set to return to the Champions League for the first time since 1980 with a 22.9 per cent chance of fourth.
They also have a 21.6 per cent possibility of getting fifth alongside Chelsea, who could claim the coveted final Champions League spot.
Fight for survival
Four teams are currently battling for their Premier League statuses ahead of next season, with all-but one going down.
Wolves have the best chance of survival as there is a 63.2 per cent chance they finish 17th.
Ipswich Town are due to head back to the Championship as an 18th-place finish has a 44.9 per cent probability.
Joining them in the second tier with a 48.7 per cent likelihood of coming 19th in the standings are Leicester City.
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And sitting rock-bottom are Southampton, who have been predicted a massive 93 per cent probability of coming last out of all 20 teams.
They have just 0.1 per cent chance of survival in 17tht - just two wins all season will do that.
Martin Keown believes Ruben Amorim has LOST the Manchester United dressing room