The Lilywhites had to settle for a 1-1 draw at Leicester City on matchday one, while the Toffees were crushed 3-0 by Brighton & Hove Albion, and here Sports Mole rounds up the team news for both clubs.
TOTTENHAM HOTSPUR vs. EVERTON
TOTTENHAM HOTSPUR
Out: Rodrigo Bentancur (head), Dominic Solanke (ankle)
Doubtful: Fraser Forster (foot)
Sports Mole's predicted XI: Vicario; Porro, Romero, Van de Ven, Udogie; Sarr, Bissouma; Kulusevski, Maddison, Son; Richarlison
EVERTON
Out: Ashley Young (suspended), Chermiti (foot), Nathan Patterson (thigh), Seamus Coleman (calf), James Garner (calf), Jarrad Branthwaite (groin)
Doubtful: James Tarkowski (unspecified)
Sports Mole's predicted XI: Pickford; Holgate, O'Brien, Keane, Mykolenko; Harrison, Iroegbunam, Doucoure, Gueye, McNeil; Calvert-Lewin
For data analysis of the most likely results, scorelines and more for this match please click here.