The Gunners will enter the contest off the back of a thumping 5-0 victory over Chelsea on Tuesday evening, and they are currently top of the table, three points clear of second-placed Liverpool.
Mikel Arteta's side have responded impressively to successive losses against Aston Villa and Bayern Munich, and the capital giants will be eyeing another huge three points this weekend.
Here, Sports Mole rounds up Arsenal's latest injury and suspension news ahead of the clash with Tottenham, who are locked in a battle with Aston Villa for fourth spot in the division.
Jurrien Timber
Status: Major doubt
Type of injury: Knee
Possible return date: April 28 (vs. Tottenham)
Timber made his long-awaited return from an ACL injury for Arsenal Under-21s against Blackburn Rovers Under-21s on Monday night, scoring a stunning goal in the contest. The Netherlands international now has a slight chance of being in the squad for the North London derby on Sunday afternoon.
ARSENAL'S SUSPENSION LIST
Arsenal have no players suspended for this match.
Utrecht 
Ajax 
Fulham 
Chelsea 
Ipswich 
Arsenal 
Manchester Utd 
Wolverhampton 
FC Augsburg 
Eintracht Frankfurt 
ST Johnstone 
Celtic 
Leicester 
Liverpool 
Borussia Dortmund 
Borussia Monchengladbach 
Bologna 
Inter 
Sevilla 
Alaves 
CSKA Moscow 
Krylya Sovetov 
FC ST. Pauli 
Bayer Leverkusen 
ST Etienne 
Lyon 
AC Milan 
Atalanta 
Real Madrid 
Athletic Bilbao 
Torino 
Udinese 
Cagliari 
Fiorentina 
Juve Stabia 
Sampdoria 
Genoa 
Lazio 
Parma 
Juventus 
Tottenham 
Nottingham Forest 
Valencia 
Espanyol 
Nantes 
Paris Saint Germain 
Manchester City 
Aston Villa 
Barcelona 
Mallorca 
Bukovina Chernivtsi 
Dynamo Kyiv 
Polissya Zhytomyr 
Shakhtar Donetsk 
Crystal Palace 
Benfica 
Tirsense