Ange Postecoglou's team drew 1-1 with Rangers in the Europa League on Thursday, while their hosts were condemned to a 1-0 loss at Aston Villa last time out, and here Sports Mole rounds up the team news for both sides.
SOUTHAMPTON vs. TOTTENHAM HOTSPUR
SOUTHAMPTON
Out: Cristian Romero (thigh), Micky van de Ven (thigh), Yves Bissouma (suspended), Rodrigo Bentancur (suspended), Wilson Odobert (hamstring), Mikey Moore (illness), Richarlison (hamstring), Ben Davies (hamstring), Guglielmo Vicario (ankle)
Doubtful: None
Sports Mole's predicted XI: Lumley; Walker-Peters, Harwood-Bellis, Wood, Bednarek, Manning; Downes, Fernandes; Dibling; Armstrong, Onuachu
TOTTENHAM HOTSPUR
Out: Jack Stephens (suspended), Aaron Ramsdale (finger), Will Smallbone (thigh), Juan Larios (unspecified), Ross Stewart (calf), Gavin Bazunu (Achilles)
Doubtful: None
Sports Mole's predicted XI: Forster; Spence, Gray, Dragusin, Udogie; Kulusevski, Sarr, Bergvall; Johnson, Solanke, Son
For data analysis of the most likely results, scorelines and more for this match please click here. Written by
Ben Knapton