While Ange Postecoglou's men will guarantee fifth with a point, their relegated hosts are condemned to a 20th-placed finish, and here Sports Mole rounds up the team news for both clubs.
SHEFFIELD UNITED vs. TOTTENHAM HOTSPUR
SHEFFIELD UNITED
Out: John Egan (ankle), Chris Basham (ankle), Oli McBurnie (thigh), Rhys Norrington-Davies (thigh), Max Lowe (ankle)
Doubtful: Andre Brooks (illness), Oliver Arblaster (calf), George Baldock (calf), Daniel Jebbison (illness), Tom Davies (thigh), Ben Osborn (thigh)
Sports Mole's predicted XI: Foderingham; Ahmedhodzic, Robinson, Trusty; Bogle, Souza, Hamer, Arblaster, Brooks; Brereton Diaz, Archer
TOTTENHAM HOTSPUR
Out: Richarlison (calf), Yves Bissouma (knee), Manor Solomon (knee), Fraser Forster (foot), Destiny Udogie (thigh), Ryan Sessegnon (hamstring), Ben Davies (calf), Timo Werner (thigh)
Doubtful: Giovani Lo Celso (knee)
Sports Mole's predicted XI: Vicario; Porro, Romero, Dragusin, Van de Ven; Sarr, Hojbjerg; Kulusevski, Maddison, Johnson; Son
For data analysis of the most likely results, scorelines and more for this match please click here.