Los Rojillos were in Copa del Rey first-round action on Tuesday evening, securing their spot in the next round of the competition courtesy of a 5-0 success over Chiclana, with Raul Garcia netting a brace for the La Liga team.
There will be wholesale changes for this game, though, with Moreno potentially selecting the same XI that took to the field for the first whistle against Real Valladolid in Spain's top flight last weekend.
Ante Budimir has again been in impressive goalscoring form this season, finding the back of the net on six occasions, and the 33-year-old is set to continue through the middle for the visitors.
Bryan Zaragoza and Ruben Pena are likely to continue in the wide areas for Osasuna, while Lucas Torro, Jon Moncayola and Aimar Oroz are set to operate in a three-man midfield.
Osasuna, who are fifth in the La Liga table, have not reported any injury problems this week, so Moreno is set to have a full complement available, with the Pamplona outfit looking to inflict a damaging defeat on the reigning Spanish and European champions.
Osasuna possible starting lineup: Herrera; Areso, Catena, Boyomo, Cruz; Moncayola, Torro, Oroz; Pena, Budimir, Zaragoza