Carlo Ancelotti's side beat Manchester City on penalties in the second leg of their quarter-final on Wednesday evening to advance to the final four of the European Cup.
Los Blancos will now switch their attention back to La Liga, where they sit top of the division, eight points clear of second-placed Barcelona ahead of El Clasico.
Here, Sports Mole rounds up Real Madrid's injury and suspension news ahead of their clash with Barcelona, who were knocked out by Paris Saint-Germain in the quarter-finals of the Champions League.
Thibaut Courtois
Status: Out
Type of injury: Knee
Possible return date: Unknown
Courtois underwent surgery on an ACL injury last August; the Belgian had been in line to return at the end of March, but it was revealed before the last international break that he had suffered another knee injury in training, leading to a further operation which has ended his campaign.
David Alaba
Status: Out
Type of injury: Knee
Possible return date: Unknown
Alaba suffered an ACL injury against Villarreal towards the end of last year, and the centre-back will not be available for the Spanish giants until the 2024-25 campaign.
Vinicius Junior
Status: Minor doubt
Type of injury: Muscle
Possible return date: April 21 (vs. Barcelona)
Vinicius will need to be assessed ahead of El Clasico, as the Brazil international had to be substituted during extra-time against Man City on Wednesday, having pulled up with a muscular issue.
Dani Carvajal
Status: Minor doubt
Type of injury: Unknown
Possible return date: April 21 (vs. Barcelona)
Carvajal also could not continue against Man City in the second leg of the Champions League quarter-final, but he is only believed to have been suffering with cramp, and Real Madrid are hopeful that the defender will be available for selection in El Clasico.
REAL MADRID'S SUSPENSION LIST
Real Madrid have no players banned for this match and will welcome Aurelien Tchouameni back into their squad, with the Frenchman missing out against Man City though suspension.