One player who remains unavailable for selection is Luke Shaw as he continues to recover from a troublesome muscle injury, while fellow defenders Victor Lindelof (groin) and Jonny Evans (knock) are both doubtful and will be assessed ahead of kickoff.
Andre Onana is expected to continue in goal ahead of number two Altay Bayindir, despite his below-par performance between the sticks in last weekend's 3-2 Premier League defeat to Nottingham Forest.
Harry Maguire and Noussair Mazraoui will be pushing to start in the back three ahead of Matthijs de Ligt and Leny Yoro, while Lisandro Martinez could continue as a left-sided centre-back to provide Amorim's defence with balance.
Tyrell Malacia was handed his first start in over 12 months in Man United's last Europa League fixture - a 3-2 win over Bodo/Glimt a fortnight ago - and he could be recalled to start at left wing-back, as Diogo Dalot, Amad Diallo and Antony all battle for a start on the right flank.
Amorim will consider freshening up his midfield, with Casemiro, Mason Mount and Christian Eriksen all in contention to start ahead of Kobbie Mainoo and Manuel Ugarte, who both began the defeat to Forest - Mainoo played the full 90 minutes.
Bruno Fernandes is another midfield option, but he may once again be tasked with operating in the front three, where Joshua Zirkzee and Marcus Rashford will be hoping for a recall at the expense of Rasmus Hojlund and Alejandro Garnacho.
Manchester United possible starting lineup: Onana; Mazraoui, Maguire, Martinez; Antony, Casemiro, Fernandes, Malacia; Mount, Rashford; Zirkzee
Written by
Oliver Thomas