Hansi Flick's side are top of the La Liga table, boasting 21 points from seven matches, while Osasuna sit in seventh, and here Sports Mole rounds up the team news for the two sides.
OSASUNA vs. BARCELONA
OSASUNA
Out: Iker Munoz (broken leg), Kike Barja (knee)
Doubtful: None
Sports Mole's predicted XI: Herrera; Areso, Boyomo, Herrando, Bretones; Moncayola, Torro, M Gomez; Zaragoza, Budimir, Oroz
BARCELONA
Out: Marc-Andre ter Stegen (knee), Fermin Lopez (leg), Dani Olmo (hamstring), Marc Bernal (knee), Andreas Christensen (Achilles), Ronald Araujo (hamstring), Frenkie de Jong (ankle), Gavi (knee)
Doubtful: None
Sports Mole's predicted XI: Pena; Kounde, Cubarsi, I Martinez, Balde; E Garcia, Pedri; Yamal, Torre, Raphinha; Lewandowski
For data analysis of the most likely results, scorelines and more for this match please click here.