The Magpies' FA Cup dream ended with a quarter-final loss to holders Manchester City two weekends ago, while the Irons were pegged back in a 1-1 draw at home to Aston Villa.
Match preview
There was not a lot to write home about during Newcastle's FA Cup quarter-final with Man City, where the Magpies cut toothless figures in the final third and were ultimately undone by two unfortunate deflections in the first half.
Bernardo Silva's 13th-minute effort took a wicked ricochet off of Dan Burn's leg and looped over a helpless Martin Dubravka, before Sven Botman inadvertently nodded another effort from the Portuguese - which may have been going wide - past his diving goalkeeper.
Missing out on a place in the FA Cup semi-finals came just five days after an equally demoralising 3-2 Premier League loss at Chelsea's Stamford Bridge base, leaving Eddie Howe's troops smack-bang in the middle of the standings in 10th position, four points worse off than their upcoming opponents.
Goals have certainly not been at a premium for Newcastle in the Premier League since the turn of the year, with a staggering 45 flying in during their nine top-flight fixtures in 2024 so far - an average of five per game - but a lack of defensive nous is severely hampering the Magpies' European bid.
Indeed, Howe's men have let in multiple goals in seven of their last nine Premier League matches and only have one top-flight clean sheet under their belts in 2024 so far, although that did come in their most recent St James' Park contest, a resounding 3-0 win over Wolverhampton Wanderers.
No visiting team has managed to prevent Newcastle from scoring at home in the current Premier League season - a bad omen for a West Ham side who have gone nine top-flight games without a clean sheet, the third-longest current run in the league behind Burnley and Sheffield United.
Amid their rearguard woes, there was no shortage of offensive firepower during the Hammers' 5-0 Europa League last-16 second-leg crushing of Freiburg, which sent David Moyes's men through to a tantalising quarter-final with Bundesliga leaders Bayer Leverkusen as they endeavour to add to their 2022-23 Europa Conference League crown.
Continental exploits may have taken their toll on both West Ham and Aston Villa on March 17, though, where Michail Antonio's diving header was cancelled out by a Nicolo Zaniolo equaliser with 11 minutes of normal time remaining in that clash of the clarets.
While the stalemate with Villa may feel like two points dropped rather than one gained for West Ham, they are now on a four-game unbeaten run in the top flight and are clinging onto seventh position in the table, although Brighton & Hove Albion have a game in hand and need only make up a two-point deficit.
However, four of West Ham's last six away matches in all tournaments have seen Moyes's men draw a blank in front of goal, and they have gone winless in their last four Premier League matches with Newcastle, requiring an 89th-minute intervention from Mohammed Kudus to rescue a 2-2 draw in October.
Newcastle United Premier League form:
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Newcastle United form (all competitions):
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West Ham United Premier League form:
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West Ham United form (all competitions):
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Team News
An excruciating evening for Sven Botman during the Man City defeat saw the Dutchman sustain a knee injury in the closing stages of that match, and he is now confirmed to have damaged his ACL, meaning that his season is over.
Botman joins Sandro Tonali (suspended), Callum Wilson (chest), Joelinton (thigh) and Nick Pope (shoulder) on the long-term absentee list, as does talented teenage midfielder Lewis Miley, who is nursing a back issue and is expected to miss around six weeks.
However, Howe is holding out hope that all of Kieran Trippier (calf), Tino Livramento (ankle) and Harvey Barnes (thigh) will be given the green light to return here; Jacob Murphy will act as an emergency right-back again if the former two cannot make it.
West Ham boss Moyes will also be forced into one change for Saturday's contest, as Edson Alvarez was booked for the 10th time in the current Premier League season against Aston Villa and will serve the first of a two-match suspension here.
Moyes's dilemma could be complicated by a fresh knee injury for Kudus, and if the Ghana man is also ruled out alongside Alvarez, both Kalvin Phillips and James Ward-Prowse should see the door swing open for returns to the starting lineup.
Maxwel Cornet (thigh) has expressed hope that he will be able to make his comeback at St James' Park, but he is unlikely to take advantage of Kudus's uncertainty - there is a spot on the bench with the former's name on it.
Newcastle United possible starting lineup:
Dubravka; Livramento, Schar, Lascelles, Burn; Willock, Guimaraes, Longstaff; Almiron, Isak, Gordon
West Ham United possible starting lineup:
Areola; Coufal, Mavropanos, Zouma, Emerson; Soucek, Phillips; Bowen, Ward-Prowse, Paqueta; Antonio
We say: Newcastle United 2-1 West Ham United
Goals on rival territory have been particularly difficult for West Ham to come by in recent times, and a fresh concern with the fitness of Kudus will do the Irons no favours whatsoever in that regard.