Heaven gets the nod over Victor Lindelof to make his full debut for the 20-time English champions, with the absences of Harry Maguire and Leny Yoro through injury opening the door for the 18-year-old to be included in the XI.
Patrick Dorgu is back on the left, with the Denmark international available amid a domestic suspension, while Alejandro Garnacho, Rasmus Hojlund and Joshua Zirkzee will operate as the front three for the Red Devils.
Manuel Ugarte is available again after a recent injury, but the Uruguay international is only on the bench.
As for Real Sociedad, the big news involves Martin Zubimendi, with the Spain international featuring in central midfield, and there will be a number of Premier League eyes on the in-demand Euro 2024 winner.
Sheraldo Becker is given the nod in the final third of the field alongside Mikel Oyarzabal and Takefusa Kubo, while on-loan West Ham United centre-back Nayef Aguerd will feature in the middle of the defence.
Manchester United: Onana; Mazraoui, De Ligt, Heaven; Dalot, Casemiro, Fernandes, Dorgu; Garnacho, Hojlund, Zirkzee
Subs: Harrison, Mee, Amass, Fredricson, Lindelof, Collyer, Eriksen, J Fletcher, Ugarte, Scanlon
Real Sociedad: Remiro; Elustondo, Zubeldia, Aguerd, Munoz; Marin, Zubimendi, Mendez; Becker, Oyarzabal, Kubo
Subs: Marrero, Barrenetxea, Oskarsson, Lopez, Olasagasti, Gomez, Traore, Aramburu, Turrientes, Martin, Beitia, Mariezkurrena
Written by
Matt Law