While Chadi Riad and Cheick Doucoure both remain sidelined with long-term knee injuries, captain Marc Guehi and Eddie Nketiah are both suspended after being sent off in last weekend's 2-1 win over Brighton & Hove Albion.
Maxence Lacroix was withdrawn as a concussion substitute last time out and has therefore emerged as a doubt, while Chris Richards will also be assessed ahead of kickoff having missed the last two games with a calf problem.
Oliver Glasner could be down to his bare bones at centre-back and if both Lacroix and Richards are to sit out along with Guehi, then the Eagles boss could be forced to select Jefferson Lerma, Joel Ward and Nathaniel Clyne in his back three, protecting Dean Henderson in goal.
Daniel Munoz is set to retain his spot at right wing-back as Ben Chilwell continues to push Tyrick Mitchell for a start on the opposite flank, while Man City-linked Adam Wharton is likely to partner either Will Hughes or Daichi Kamada in centre-midfield.
Glasner is unlikely to make any changes in the final third, with both Eberechi Eze and Ismaila Sarr expected to provide support in attack for central striker Jean-Philippe Mateta, who is hoping to end his four-game goal drought away from home.
Crystal Palace possible starting lineup: Henderson; Lerma, Lacroix, Richards; Munoz, Wharton, Hughes, Mitchell; Sarr, Eze; Mateta
Written by
Oliver Thomas