The Citizens have kick-started the defense of their top-flight crown with three successive wins over Chelsea, Ipswich Town and West Ham United, ending the month of August by beating the latter 3-1 away from home just before the international break.
Brentford, meanwhile, have picked up six points from their opening three Premier League games, most recently beating Southampton by a 3-1 scoreline on home soil.
Here, Sports Mole takes an in-depth look at the head-to-head record and previous meetings between the two sides.
Head-to-head record
Previous meetings: 19
Man City wins: 11
Draws: 1
Brentford wins: 7
Man City and Brentford have butted heads a total of 19 times across all competitions, with the Citizens leading the head-to-head record having posted 11 wins to the Bees' seven, while there has also been just the one draw between these two teams.
You have to go back 92 years for the very first encounter between these two teams when Man City put Brentford to the sword 6-1 at Maine Road in the fourth round of the FA Cup. Fred Tilson scored a hat-trick, while Eric Brook (2) and Dave Halliday were also on the scoresheet for the Citizens.
Man City won four and drew one of their first five meetings with Brentford before the Bees celebrated their first triumph in December 1937, winning 2-0 away from home in the old First Division.
That victory for Brentford was the first of five in six games over a 52-year period, including FA Cup and League Cup successes in 1989, but the tables have since turned in Man City's favor as they have come out on top in six of the last eight meetings in all competitions.
Since Brentford secured promotion to the Premier League in 2021, they have beaten Man City just twice, both home and away in the 2022-23 campaign when the Citizens went on to win a historic treble.
One of the Bees' standout results from that season was their 2-1 victory at the Etihad Stadium in November 2022 when Ivan Toney netted a memorable brace, including a dramatic stoppage-time winner.
Since then, Man City have won their last two encounters with Brentford. Phil Foden scored a sublime hat-trick in a 3-1 away victory in February 2024, and just 15 days later, Erling Haaland scored the only goal in a slender 1-0 win for Pep Guardiola's men on home soil.
Previous 10 meetings
Feb 20, 2024: Man City 1-0 Brentford (Premier League)
Feb 05, 2024: Brentford 1-3 Man City (Premier League)
May 28, 2023: Brentford 1-0 Man City (Premier League)
Nov 12, 2022: Man City 1-2 Brentford (Premier League)
Feb 09, 2022: Man City 2-0 Brentford (Premier League)
Dec 29, 2021: Brentford 0-1 Man City (Premier League)
Jan 25, 1997: Brentford 0-1 Man City (FA Cup Third Round)
Oct 4, 1989: Man City 4-1 Brentford (EFL Cup Second Round Second Leg)
Sep 19, 1989: Brentford 2-1 Man City (EFL Cup Second Round First Leg)
Jan 28, 1989: Brentford 3-1 Man City (FA Cup Fourth Round)
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