The Citizens played out an enthralling 1-1 draw with fellow title rivals Liverpool at Anfield before the international break, extending their unbeaten run in all competitions to 22 matches.
With 10 Premier League games remaining, Pep Guardiola's men sit third in the table and only one point behind both second-placed Liverpool and leaders Arsenal, who beat Brentford 2-1 in their last top-flight fixture and sit pretty at the summit by virtue of a superior goal difference.
Man City have had their fair share of injury concerns following the international break, and here, Sports Mole rounds up their latest injury and suspension news ahead of the contest with Mikel Arteta's side.
Kyle Walker
Status: Major doubt
Type of injury: Hamstring
Possible return date: March 31 (vs. Arsenal)
Kyle Walker was forced off with a hamstring injury in the first half of England's 1-0 friendly defeat to Brazil and later withdrew from the Three Lions squad. The defender missed first-team training on Thursday and has emerged as a serious doubt for Sunday's game.
John Stones
Status: Major doubt
Type of injury: Groin
Possible return date: March 31 (vs. Arsenal)
John Stones was also substituted early on England duty in a 2-2 draw with Belgium on Tuesday after picking up a groin issue, and it remains to be seen whether the defender, who also missed training on Thursday, will be fit to feature against Arsenal.
Manuel Akanji
Status: Minor doubt
Type of injury: Knock
Possible return date: March 31 (vs. Arsenal)
Manuel Akanji has emerged as a doubt for Sunday's game after he withdrew from the Switzerland squad earlier this week due to a knock, but he did take part in training on Thursday.
Matheus Nunes
Status: Minor doubt
Type of injury: Foot
Possible return date: March 31 (vs. Arsenal)
Matheus Nunes was not involved in Portugal's friendly defeat to Slovenia as he required treatment for a knock to his foot, but the midfielder returned to Man City training on Thursday and could be fit to return to the matchday squad on Sunday.
Kevin De Bruyne
Status: Minor doubt
Type of injury: Groin
Possible return date: March 31 (vs. Arsenal)
Kevin De Bruyne was omitted from the Belgium squad earlier this month due to a groin problem, but the playmaker has since been pictured in training this week and could therefore be ready to return against Arsenal.
Jack Grealish
Status: Minor doubt
Type of injury: Groin
Possible return date: March 31 (vs. Arsenal)
Jack Grealish has also been spotted in training this week and could be fit to feature on Sunday following a spell on the sidelines with a groin injury.
Ederson
Status: Minor doubt
Type of injury: Muscle
Possible return date: March 31 (vs. Arsenal)
First-choice goalkeeper Ederson picked up a muscle injury in Man City's 1-1 draw with Liverpool before the international break, and although reports following that match suggested he would be sidelined for up to four weeks, the Brazilian took part in first-team training on Thursday.
MANCHESTER CITY'S SUSPENSION LIST
Manchester City have no suspended players for this match.