The Reds conquered AC Milan 3-1 in their first European affair of the season and most recently sunk Wolverhampton Wanderers 2-1 in Saturday's Premier League clash, propelling them back to the top of the table.
However, Darwin Nunez was ruled out of that victory at the last minute through illness, while Andrew Robertson was the victim of a heavy tackle from Carlos Forbs in the dying embers and is now a doubt for this battle, which Harvey Elliott (foot) will also miss.
Nunez's infection is likely to clear up in time for the visit of Bologna, though, and he could now join forces with Dominik Szoboszlai and Mohamed Salah, the latter of whom could become the first Liverpool man to score in five straight Champions League home games.
Slot may reward Cody Gakpo for his late assist against Milan with a start over Luis Diaz on the left, though, while Alexis Mac Allister and Ryan Gravenberch are immovable in midfield.
The Liverpool boss is hopeful that Robertson has avoided a serious problem, but Kostas Tsimikas is waiting in the wings after starting the win over Milan, where he did not cover himself in glory for Christian Pulisic's opener.
However, Virgil van Dijk, Trent Alexander-Arnold and Ibrahima Konate should all hold their spots ahead of Alisson Becker, who returned from a brief injury absence at Molineux.
Liverpool possible starting lineup:
Alisson; Alexander-Arnold, Van Dijk, Konate, Tsimikas; Gravenberch, Mac Allister; Salah, Szoboszlai, Gakpo; Nunez