The hosts are two points above the relegation zone, while the visitors are four points behind in the title race.
Match preview
Konyaspor lost 1-0 to Sivasspor at the Yeni 4 Eylul Stadyumu last Saturday, making it two defeats in a row for the Anatolian Eagles and leaving their top-flight status in jeopardy.
Fahrudin Omerovic's men saw their resistance broken in the 86th minute when Rey Manaj found the net for Sivas and they could not find a way back into the game.
With 36 points amassed from their 34 league outings this term, Konyaspor sit 16th in the standings, just two points clear of the relegation zone.
Having picked up 19 points from 16 home matches, the third-lowest number of points on home soil by a side in this campaign, Monday's hosts will be hoping to find a way to stop an opposition that has dominated them.
In 24 meetings between both sides at Torku Arena, Konyaspor have lost 15 times, winning seven and drawing twice.
Fenerbahce returned to winning ways with a 2-1 victory over ten-man Besiktas, courtesy of goals from Michy Batshuayi and Irfan Kahveci.
Ismail Kartal's men remain four points adrift of city rivals Galatasaray at the summit of the Turkish Super Lig table, with four matches left to play.
The Yellow Canaries are the best side on the road this season and remain the only team without an away defeat so far. They are unbeaten in 17 away matches in this campaign, with 15 wins and two draws.
Having dominated the last two meetings between both sides, scoring 11 goals and conceding just one, they will be hoping to record a similar result while keeping tabs on Gala for the chance to close the gap if there is a slip-up.
Konyaspor Turkish Super Lig form:
D
D
L
W
L
L
Fenerbahce Turkish Super Lig form:
W
W
W
W
D
W
Fenerbahce form (all competitions):
W
L
W
L
D
W
Team News
Konyaspor will be without Valon Ethemi and Bouly Junior Sambou, who are both suspended for this clash due to accumulated yellow cards.
Metehan Mert, Karahan Yasir Subasi and Emmanuel Boateng are out with groin, thigh and muscle injuries respectively.
Sokol Cikalleshi has 11 goals in the league this season and will be looking to add to it when he leads the line on Monday.
The visitors will be without Jayden Oosterwolde and Ryan Kent, who are both sidelined with knee injuries.
Edin Dzeko is second on the scorer's chart with 20 goals and will hope to return to the XI after starting from the bench last time out.
Konyaspor possible starting lineup:
Slowik; Oguz, Demirbag, Damjanovic, Guilherme; Dikmen, N'Zonzi; Ndao, Prip, Cicaldau; Cikalleshi
Fenerbahce possible starting lineup:
Livakovic; Kadioglu, Djiku, Becao, Osayi-Samuel; Fred, Yuksek; Tadic, Szymanski, Kahveci; Dzeko