The reigning La Liga champions will enter the contest off the back of a 4-2 victory over Valencia, with the team bouncing back from successive losses to Paris Saint-Germain and Real Madrid.
Barcelona did not pick up any fresh fitness problems against Valencia, but Gavi and Alejandro Balde remain long-term absentees due to knee and hamstring injuries respectively.
Meanwhile, Frenkie de Jong is unlikely to play again this season due to the ankle injury which he suffered in the recent league defeat to Real Madrid.
However, there is believed to be a chance that the Netherlands international will be able to represent his country at this summer's European Championship.
Pedri dropped down to the bench against Valencia, but he is expected to come back into the side here in place of Fermin Lopez, who was on the scoresheet last time out.
Robert Lewandowski struck a hat-trick against Los Che and will continue as the centre-forward, with Lamine Yamal and Raphinha again set to join him in the final third of the field.
Meanwhile, Andreas Christensen should continue in central midfield on Saturday night.
Barcelona possible starting lineup: Ter Stegen; Kounde, Araujo, Cubarsi, Cancelo; Gundogan, Christensen, Pedri; Yamal, Lewandowski, Raphinha
Bologna 
Napoli 
Leicester 
Newcastle 
Arsenal 
Real Madrid 
Bayern Munich 
Inter 
Barcelona 
Borussia Dortmund 
Paris Saint Germain 
Aston Villa 
Tirsense 
Benfica 
Bodo/Glimt 
Lazio 
Legia Warszawa 
Chelsea 
Lyon 
Manchester Utd 
Rangers 
Athletic Bilbao 
Tottenham 
Eintracht Frankfurt 
NK CM Celje 
Fiorentina 
Cherkasi 
Shakhtar Donetsk 
Spartak Moscow 
FK Makhachkala 
Nimes 
Bordeaux 
VFL Wolfsburg 
RB Leipzig 
Udinese 
AC Milan 
Valencia 
Sevilla 
Orenburg 
CSKA Moscow 
Kryvbas Kryvyi Rih 
Dynamo Kyiv 
Manchester City 
Crystal Palace 
Celtic 
Kilmarnock 
Bayer Leverkusen 
Union Berlin 
Brighton 
Nottingham Forest 
Everton 
Rubin 
Lokomotiv Moscow 
Fortuna Sittard 
Feyenoord 
Monaco 
Marseille 
Sampdoria 
Cittadella