The Lions are currently fifth in the table, six points behind fourth-placed Atletico Madrid, while Getafe are 10th, six points behind seventh-placed Real Betis in the race for Europe.
Match preview
Getafe have finished 15th in each of their last three campaigns in Spain's top flight, so there has been a huge improvement this season, with the capital outfit currently sitting in 10th position in the division.
Jose Bordalas's side are only actually six points behind seventh-placed Real Betis, so a late push for Europe cannot be ruled out, and they will enter this match off the back of a 3-1 success at Almeria.
Getafe have only lost one of their last five games in Spain's top flight, and a positive result on Friday would lead them nicely into their next fixture against struggling Cadiz on May 12.
The Deep Blue Ones have been strong at home this season, picking up 29 points from their 16 matches in front of their own fans, recording eight victories in the process.
Getafe are unbeaten in their last five La Liga games against Athletic, meanwhile, with each of those fixtures finishing level, including a 2-2 draw in the reverse match at San Mames earlier this season.
Athletic have won just one of their last 13 La Liga matches against Getafe, meanwhile, with that success coming on home soil in January 2021, and 10 of their last 13 league meetings have ended all square.
A draw is no good for the Lions on Friday, though, with a win required if they are to remain in the hunt for a top-four finish, as a damaging 3-1 loss occurred to Atletico last time out.
Athletic are fifth in the table, six points behind fourth-placed Atletico with five games left, so they will need to be almost perfect in the final stages of the campaign and then hope that Atletico slip up.
That said, fifth, and automatic qualification for the group stage of next season's Europa League, would represent a strong campaign for Ernesto Valverde's side.
The Basque outfit have finished eighth in their last two La Liga campaigns, while they have not been higher than seventh since 2015-16, with their last top-four finish occurring 10 years ago.
Athletic have played their best football at San Mames this season, but the Copa del Rey winners have also picked up a respectable 20 points from their 16 matches on their travels.
Getafe La Liga form:
L
W
L
D
D
W
Athletic Bilbao La Liga form:
W
W
L
D
D
L
Athletic Bilbao form (all competitions):
W
L
W
D
D
L
Team News
Getafe will be missing five players due to injury problems, with Mauro Arambarri, Juan Iglesias, Carles Alena, Domingos Duarte and Borja Mayoral out of Friday's contest in the Spanish capital.
Mason Greenwood scored twice in the success over Almeria last time out, and he is again set to feature down the right, but there could be a change at centre-forward, with Jaime Mata pushing to come back in.
Oscar Rodriguez should retain his spot down the left for the home side, while there is likely to be another start in the number 10 position for Nemanja Maksimovic.
As for Athletic, Inigo Ruiz de Galarreta will miss out with the thigh problem that he suffered during the contest with Atletico last time out.
Yuri Berchiche is also set to remain on the sidelines, but the squad will be boosted by the return of Oscar de Marcos, who was suspended against Diego Simeone's side.
Dani Vivian played at right-back against Atletico, but De Marcos's return will allow him to return to the middle of the defence, while Mikel Vesga should replace Ruiz de Galarreta in midfield.
There are unlikely to be any changes in the final third of the field, though, with Inaki Williams, Oihan Sancet and Nico Williams again set to operate behind Gorka Guruzeta.
Getafe possible starting lineup:
Soria; Carmona, Dakonam, Alderete, Rico; Moriba, Milla; Greenwood, Maksimovic, Rodriguez; Mata
Athletic Bilbao possible starting lineup:
Simon; De Marcos, Vivian, Paredes, Lekue; Vesga, Benat; I Williams, Sancet, N Williams; Guruzeta
We say: Getafe 1-1 Athletic Bilbao
This fixture produces draws, plenty of them. On paper, Athletic are the favourites, but Getafe have been strong at home this season, while Athletic are inconsistent on their travels. It would not be a shock to see a home or indeed an away win, but we have had to settle on a low-scoring draw here.