Both making the net ripple off the bench versus Steve Clarke's troops, Wout Weghorst and Donyell Malen are pushing for starts at the focal point of Oranje's attack, however Memphis Depay is a certain starter for the beginning of Euro 2024 and should retain his spot in Frankfurt.
Netting his first-ever goal on the international stage, Tijjani Reijnders may well have played his way into another XI for the Netherlands on Tuesday, although there could be changes elsewhere in the engine room, with Mats Wieffer potentially being relegated to the bench for Joey Veerman.
Enjoying an unbeaten campaign with Xabi Alonso's Bayer Leverkusen, Jeremie Frimpong featured in an unnatural right-back role on Friday night and is expected to drop out here, with first-choice full-back Denzel Dumfries proving an attacking nuisance for opponents during recent major tournaments.
Even though the quality of his opposition in club football is coming under increasing scrutiny, Georginio Wijnaldum came up with the goods against Scotland as he doubled the Netherlands' advantage in the contest after 72 minutes, and the former Liverpool man should start again in this one.
With Stefan de Vrij returning to club side Inter Milan due to an injury, the position alongside Virgil van Dijk is set to be hotly contested ahead of Tuesday's trip to Germany, with Lutsharel Geertruida currently ahead of Bayern Munich's Matthijs de Ligt in the pecking order.
Quilindschy Hartman joins De Vrij as an Oranje player who dropped out of the squad earlier in the international window due to a fitness issue, meaning that Nathan Ake will continue to play the left side of the visitors' backline, showcasing the versatility drilled into him under Pep Guardiola at Manchester City.
Netherlands possible starting lineup: Flekken; Dumfries, Geertruida, Van Dijk, Ake; Veerman, Wijnaldum, Reijnders; Simons, Gakpo, Depay