Joachim Andersen will serve a one-match suspension after being sent off in the 3-1 defeat at home to Aston Villa last weekend, while Sasa Lukic and Timothy Castagne remain sidelined with respective shoulder and hamstring injuries.
Marco Silva has confirmed that Jorge Cuenca (ankle) and Carlos Vinicius (calf) "are going in the right direction" in their recovery from injury and both players will be assessed ahead of kickoff.
In the absence of Andersen, Issa Diop is expected to start in central defence alongside Calvin Bassey, while Kenny Tete and Antonee Robinson are set to continue as full-backs.
Andreas Pereira, who missed a first-half penalty in the defeat to Villa, will likely retain his spot in centre-midfield alongside Sander Berge, although Harrison Reed and Tom Cairney will be hoping to force their way into the starting lineup.
Raul Jimenez has scored three goals in his last four Premier League appearances and is expected to continue up front, with Rodrigo Muniz providing cover on the substitutes' bench, while Adama Traore, Emile Smith Rowe and former Everton winger Alex Iwobi should all offer support in the final third.
Fulham possible starting lineup: Leno; Tete, Diop, Bassey, Robinson; Berge, Pereira; Traore, Smith Rowe, Iwobi; Muniz
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