Chelsea, who finished sixth in the top flight last season, are beginning a new era under head coach Enzo Maresca, who has succeeded Mauricio Pochettino after winning the Championship title with Leicester City in 2023-24.
Man City, meanwhile, are bidding to create more history this term after winning an unprecedented fourth consecutive Premier League title last season, finishing two points clear of their nearest challengers Arsenal.
Pep Guardiola's men beat Chelsea 4-2 in a pre-season friendly earlier this month and will endeavour to claim another statement victory over the Blues in the capital.
Ahead of the enticing contest at Stamford Bridge, Sports Mole takes a closer look at the head-to-head record between the clubs.
Head-to-head record
Previous meetings: 178
Manchester City wins: 66
Draws: 41
Chelsea wins: 71
Man City and Chelsea have locked horns a total of 178 times, with the West Londoners marginally leading the overall head-to-head record as they have won 71 games compared to the Citizens' 66, while 41 draws have been played out between the two clubs.
You have to go back 116 years for the very first encounter between these two teams, who played out a 2-2 draw in the top flight in front of 40,000 fans at Stamford Bridge back in December 1907.
In the Premier League era (since 1992-93), Chelsea have come out on top in 27 of their 54 meetings with Man City, losing 18 matches and drawing nine, but the Citizens have bested the Blues in six of their nine FA Cup encounters and have also won three out of four EFL Cup meetings, including one via a penalty shootout in the 2019 final.
The only other occasion when these two sides have faced off in a final of a major competition was in May 2021 when a first-half goal from Kai Havertz helped Chelsea secure a narrow 1-0 win over Man City in the Champions League showpiece event held in Istanbul.
Chelsea were the dominant side in this fixture with Man City during the first half of the Premier League era, as they registered 18 victories out of 24 and scored 45 goals in the process - their longest-ever winning run against the Citizens was an eight-match streak between December 2005 and March 2009.
However, the tides have since shifted into Man City's favour as they have come out on top in 16 of the last 30 top-flight battles with Chelsea, scoring a total of 47 goals. The West Londoners, meanwhile, have won nine times during this period and there have also been five draws.
Chelsea have failed to win any of their last nine meetings with Pep Guardiola's side in all competitions, losing six games in a row immediately after their aforementioned Champions League triumph over the Citizens in 2021, before playing out two entertaining draws in the 2023-24 Premier League season.
One of the most enthralling top-flight games of that campaign took place at Stamford Bridge when Chelsea and Man City shared the spoils in a 4-4 draw; Rodri thought he had won it for the visitors with an 86th-minute strike, but ex-City man Cole Palmer had the last laugh as he converted a 94th-minute penalty to salvage a point for the Blues.
There was nothing to separate the two teams in the reverse fixture at the Etihad Stadium in February, as Rodri netted in the 83rd minute to cancel out a first-half strike from former Man City attacker Raheem Sterling and force a spirited Chelsea outfit to settle for only a point.
The most recent meeting between the two teams was in the FA Cup semi-finals at Wembley in April 2024, when a late deflected strike from Bernardo Silva secured a slender 1-0 win for Man City against a wasteful Chelsea outfit.
Man City legend Sergio Aguero is the all-time leading scorer in this fixture with 13 goals in 21 games, including two Premier League hat-tricks, while Frank Lampard, who represented both the Citizens and Chelsea, is next on the list with eight goals, including seven for the West Londoners. Former Chelsea forward Jimmy Greaves and ex-Man City duo Carlos Tevez and Francis Lee all scored six times.
Last 20 meetings:
Apr 20, 2024: Man City 1-0 Chelsea (FA Cup Semi-Finals)
Feb 17, 2024: Man City 1-1 Chelsea (Premier League)
Nov 12, 2023: Chelsea 4-4 Man City (Premier League)
May 21, 2023: Man City 1-0 Chelsea (Premier League)
Jan 8, 2023: Man City 4-0 Chelsea (FA Cup Third Round)
Jan 5, 2023: Chelsea 0-1 Man City (Premier League)
Nov 9, 2022: Man City 2-0 Chelsea (EFL Cup Third Round)
Jan 15, 2022: Man City 1-0 Chelsea (Premier League)
Sep 25, 2021: Chelsea 0-1 Man City (Premier League)
May 29, 2021: Man City 0-1 Chelsea (Champions League Final)
May 8, 2021: Man City 1-2 Chelsea (Premier League)
Apr 17, 2021: Chelsea 1-0 Man City (FA Cup Semi-Finals)
Jan 3, 2021: Chelsea 1-3 Man City (Premier League)
Jun 25, 2020: Chelsea 2-1 Man City (Premier League)
Nov 23 2019: Man City 2-1 Chelsea (Premier League)
Feb 24, 2019: Chelsea 0-0 Man City - 3-4 on penalties (EFL Cup Final)
Feb 10, 2019: Man City 6-0 Chelsea (Premier League)
Dec 8, 2018: Chelsea 2-0 Man City (Premier League)
Aug 5, 2018: Chelsea 0-2 Man City (Community Shield)
Mar 4, 2018: Man City 1-0 Chelsea (Premier League)
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