Enso Gonzalez, Yerson Mosquera and Leon Chiwome are all ruled out for the rest of the season with long-term knee injuries, while Sasa Kalajdzic is still recovering from a knee problem of his own but is targeting a return before the season comes to a close.
January signing Emmanuel Agbadou is seemingly facing a spell on the sidelines after pulling his hamstring in Wolves' 2-1 defeat at Liverpool last weekend, while Sam Johnstone, Rodrigo Gomes (both unspecified) and Hwang Hee-Chan (hamstring) will all be assessed after missing the loss at Anfield.
On a positive note, Vitor Pereira has been boosted by the return to training of Jorgen Strand Larsen and he could be fit to return to the matchday squad, although it remains to be seen whether he is ready to be thrown straight back into the first XI.
Goncalo Guedes could therefore continue to lead the, although he was withdrawn at half time against Liverpool, with new midfielder Marshall Munetsi surprisingly brought on to operate as a makeshift forward. Whether Pereira begins with the Zimbabwean down the middle on Saturday remains to be seen.
One player who is all but certain to start in attack is star man Matheus Cunha, who scored for the third successive game in the defeat to Liverpool, increasing his PL goal tally for the season to 12, while Joao Gomes and Andre are set to continue in midfield.
Nelson Semedo and Rayan Ait-Nouri are the most likely duo to operate as wing-backs, while the expected absence of Agbadou could see Santiago Bueno handed a start in central defence alongside Matt Doherty and Toti Gomes.
Wolverhampton Wanderers possible starting lineup: Sa; Doherty, S. Bueno, Toti; Semedo, J. Gomes, Andre, Ait-Nouri; Sarabia, Cunha; Guedes
Written by
Oliver Thomas