Hansi Flick's side will enter the match off the back of a 3-0 victory over Brest in the Champions League, but they have only picked up one point from their last two league games against Real Sociedad and Celta Vigo.
Barcelona are currently top of the La Liga table, four points clear of second-placed Real Madrid, who have a game in hand, while Las Palmas occupy 17th, just two points outside of the relegation zone.
Here, Sports Mole takes an in-depth look at the head-to-head record and previous meetings between the two sides ahead of their contest at Estadi Olimpic Lluis Companys.
Head-to-head record
Previous meetings: 77
Barcelona wins: 49
Draws: 8
Las Palmas wins: 20
Barcelona and Las Palmas have locked horns on 77 occasions throughout history, and unsurprisingly the former have been the dominant side in this fixture, posting 49 wins to the latter's 20, while there have also been eight draws.
The Catalan giants are unbeaten against Las Palmas in all competitions since February 1991, with that clash taking place in the last-16 stage of the Copa del Rey, but Barcelona still advanced to the next round courtesy of a 6-1 aggregate win.
Not since February 1986 have Las Palmas overcome Barcelona in the league, which is an indication of the size of their task on Saturday, with the hosts enjoying a lot of success in their recent meetings.
Barcelona posted 2-1 and 1-0 victories in their La Liga matches last season, but the two teams did play out a 1-1 draw in a league fixture back in March 2018.
The Catalan team have won seven of their last eight matches with Las Palmas, while they have been victorious in 43 of their previous 70 games in La Liga, suffering 19 defeats in the process.
Las Palmas have not beaten Barcelona away from home in the league since September 1971, although this weekend's match will not take place at Camp Nou, which should hand them a degree of confidence.
Eulogio Martinez is the all-time leading goalscorer in this particular fixture, scoring nine times for Barcelona against Las Palmas; the Paraguayan turned out for the Catalan team between 1956 and 1962, and he certainly enjoyed taking on Los Amarillos.
Last 20 meetings
Mar 30, 2024: Barcelona 1-0 Las Palmas (La Liga)
Jan 04, 2024: Las Palmas 1-2 Barcelona (La Liga)
Mar 01, 2018: Las Palmas 1-1 Barcelona (La Liga)
Oct 01, 2017: Barcelona 3-0 Las Palmas (La Liga)
May 14, 2017: Las Palmas 1-4 Barcelona (La Liga)
Jan 14, 2017: Barcelona 5-0 Las Palmas (La Liga)
Feb 20, 2016: Las Palmas 1-2 Barcelona (La Liga)
Sep 26, 2015: Barcelona 2-1 Las Palmas (La Liga)
Mar 03, 2002: Barcelona 1-1 Las Palmas (La Liga)
Nov 17, 2001: Las Palmas 0-0 Barcelona (La Liga)
Apr 01, 2001: Barcelona 4-1 Las Palmas (La Liga)
Nov 04, 2000: Las Palmas 0-1 Barcelona (La Liga)
Apr 03, 1997: Barcelona 3-0 Las Palmas (Copa del Rey Semi-Finals Second Leg)
Mar 26, 1997: Las Palmas 0-4 Barcelona (Copa del Rey Semi-Finals First Leg)
Feb 27, 1991: Barcelona 6-0 Las Palmas (Copa del Rey Last-16 Second Leg)
Feb 06, 1991: Las Palmas 1-0 Barcelona (Copa del Rey Last-16 First Leg)
Jan 31, 1988: Barcelona 1-1 Las Palmas (La Liga)
Aug 30, 1987: Las Palmas 1-2 Barcelona (La Liga)
Feb 22, 1987: Las Palmas 0-0 Barcelona (La Liga)
Oct 26, 1986: Barcelona 4-0 Las Palmas (La Liga)
Last 10 La Liga meetings
Mar 30, 2024: Barcelona 1-0 Las Palmas (La Liga)
Jan 04, 2024: Las Palmas 1-2 Barcelona (La Liga)
Mar 01, 2018: Las Palmas 1-1 Barcelona (La Liga)
Oct 01, 2017: Barcelona 3-0 Las Palmas (La Liga)
May 14, 2017: Las Palmas 1-4 Barcelona (La Liga)
Jan 14, 2017: Barcelona 5-0 Las Palmas (La Liga)
Feb 20, 2016: Las Palmas 1-2 Barcelona (La Liga)
Sep 26, 2015: Barcelona 2-1 Las Palmas (La Liga)
Mar 30, 2002: Barcelona 1-1 Las Palmas (La Liga)
Nov 17, 2001: Las Palmas 0-0 Barcelona (La Liga)
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