The Catalan giants, who are guaranteed a last-16 place, are sitting in second place with 18 points to their name, leaving them three points adrift of leaders Liverpool.
Hansi Flick's side will be full of confidence after they followed last week's 5-4 comeback win over Benfica with a thumping 7-1 victory over Valencia in Sunday's La Liga clash.
Here, Sports Mole rounds up Barcelona's injury and suspension news ahead of the clash with Atalanta, who are in seventh place after collecting 14 points from their seven matches in the league phase.
Dani Olmo
Status: Major doubt
Type of injury: Calf
Possible return date: January 29 (vs. Atalanta)
Olmo has been forced to miss Barcelona's last two matches with a calf injury, and he faces a race against time to prove his time for Wednesday's fixture, especially after he missed Monday's training training session.
Inigo Martinez
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Martinez has been sidelined since he was forced off in the first half of the Spanish Super Cup final against Real Madrid earlier this month. The defender's hamstring problem is expected to keep him out of action until mid to late February.
Marc Bernal
Status: Out
Type of injury: Knee
Possible return date: Unknown
Bernal is a long-term absentee after he sustained an ACL injury in a La Liga meeting with Rayo Vallecano in August. The midfielder is set to miss the remainder of the season, and will be focusing on returning to fitness ahead of the 2025-26 campaign.
Marc-Andre ter Stegen
Status: Out
Type of injury: Knee
Possible return date: Unknown
Like Bernal, Ter Stegen is unlikely to play again this season, having been sidelined since September with a serious knee injury, leading the club to bring Wojciech Szczesny out of retirement to cover the German's absence.
BARCELONA'S SUSPENSION LIST
Barcelona have no players suspended for the Champions League encounter.
Written by
Ben Sully