Isaac Asante (born 21 August 2002) is a Ghanaian professional footballer who plays for OH Leuven in the Belgian First Division A.
After several first-team players had become injured in the previous match, Asante made his professional debut for OH Leuven on 15 August 2020 in the away match against Genk, ending 1–1. He started the match and was subbed off just after the hour mark, being replaced by Yohan Croizet.